Clinical Micro Sensors, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-La Roche Ag

Christine J Shaw

Anna Maria Al-Khouri

Bradley Adam Brown

Lisa Lynn Freeman-Cook

Milena Iacobelli Martinez

John Jay Harvey

Michael Thomas Nguyen

The present disclosure relates to methods and devices for amplifying a plurality of targets in a single PCR run while distinguishing between clinically relevant amplification and amplification from other sources such as from background contamination. The methods and devices further enable discrimination between gram-positive, gram-negative and fungal infections as wells as identify antimicrobial resistance genes. When applying the methods and devices of the invention, the species or genus of an infection(s), and genus of a fungal co-infection(s) or category of bacterial (gram-positive or negative) co-infection(s) are identified. Species identification of co-infections can also be achieved. Further, when applying the methods and devices of the invention, organisms which are likely to be contaminating organisms from a blood draw are identified.

Electrochemical detection of bacterial and/or fungal infections

Growing community of inventors

San Diego, CA, United States of America

Christine J Shaw