Delta Biotechnology Limited

Christine J Fleming

Edward Hinchliffe

Yeast is genetically modified by transformation with an integration vector comprising two copies of a homologous 2 .mu.m plasmid DNA sequence in direct orientation relative to one another and encompassing the said DNA sequence, and then isolating, from the transformed yeast obtained, cells containing the endogenous 2 .mu.m plasmid modified by incorporation of the said DNA sequence but not containing the said vector. The resulting yeast can be maintained under non-selective growth conditions.

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Leicestershire, United Kingdom

Christine J Fleming