Biomerieux, Inc.

Biomerieux Sa

Institut National De La Sante Et De La Recherche Medicale

Université´ D'aix-Marseille

Service De Santé Des Armées (ssa)

Christine Franceschi

Jean-Philippe Charrier

Yannick Charretier

Gilles Zambardi

Tiphaine Cecchini

Elodie Degout-Charmette

Corinne Beaulieu

Sylvie Pons

Victoria Girard

Sonia Chatellier

Philippe Dufour

Jean-Marie Pages

Elizabeth Pinet

A method for characterizing at least one microorganism from a sample includes identifying the at least one microorganism and determining the properties of typing, potential resistance to at least one antimicrobial, and virulence factor. The properties of typing, resistance to at least one antimicrobial, and virulence factor for the at least one microorganism are determined by implementing mass spectrometry using proteins, peptides and/or metabolites as markers of the properties of typing, resistance to at least one antimicrobial, and virulence factor.

Method for characterizing at least one microorganism by means of mass spectrometry

A method of detection, for at least one microorganism contained in a sample, of at least one marker of resistance to a glycopeptide, including the detection, by mass spectrometry, of at least one peptide or protein of the microorganism. Preferably, the glycopeptide is vancomycin. Preferably, the peptide is derived from a protein of type vanA, vanB, vanC, vanD, vanE, vanG, vanL, vanM or vanN.

Method for detecting at least one mechanism of resistance to glycopeptides by mass spectrometry

The present invention pertains to a method of detection, by mass spectrometry, of at least one marker of at least one mechanism of resistance to at least one antimicrobial, resistance of at least one microorganism contained in a sample, characterized in that the antimicrobial is a carbapenem, and said resistance markers are proteins or peptides. Preferably, said proteins or peptides are proteins from said microorganism.

Method of detecting at least one mechanism of resistance to carbapenems by mass spectrometry

The present invention pertains to a method of detection, by mass spectrometry, of at least one marker of at least one mechanism of resistance to at least one antimicrobial, resistance of at least one microorganism contained in a sample, characterised in that the antimicrobial is a cephalosporin, and said resistance markers are proteins or peptides. Preferably, said proteins or peptides are proteins from said microorganism.

Method of detecting at least one mechanism of resistance to cephalosporins by mass spectrometry

The present invention pertains to a method of detection, by mass spectrometry, of at least one marker of at least one mechanism of resistance to at least one antimicrobial, resistance of at least one microorganism contained in a sample, characterised in that the antimicrobial is a carbapenem, and said resistance markers are proteins or peptides. Preferably, said proteins or peptides are proteins from said microorganism.

The present invention pertains to a method of detection, by mass spectrometry, of at least one marker of at least one mechanism of resistance to at least one antimicrobial, resistance of at least one microorganism contained in a sample, characterized in that the antimicrobial is a cephalosporin, and said resistance markers are proteins or peptides. Preferably, said proteins or peptides are proteins from said microorganism.

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Meximieux, France

Christine Franceschi