Samsung Electronics Co., Ltd.

Samsung Bioepis Co., Ltd.

Christina Yi

Seung Hyun Lee

Kwang Ho Cheong

Mi Young Cho

Young Jun Koh

Jae Woong Hwang

Powei Lin

Hye Young Suh

Sunkyu Kim

Lin Powei

Eunyoung Park

Hee Kyung Sung

Provided is a recombinant cell including inactivated pyruvate dehydrogenase kinase (PDK) gene, a composition for producing a polypeptide of interest including the recombinant cell, and a method of producing a polypeptide of interest using the recombinant cell.

Method for producing polypeptides using PDK-inactivated cells

There are provided an anti-c-Met/anti-Her2 bispecific antibody, and a method for preventing and/or treating cancer using the same.

Bispecific anti-Cmet/anti-Her2 antibodies

There are provided an anti-c-Met/anti-EGFR bispecific antibody, a method for treating cancer using the same, and an anti-EGFR scFv fragment.

Anti-c-Met/anti-EGFR bispecific antibodies

A method of target membrane protein depletion comprising treating a cell with a dual binding molecule comprising a first binding domain which binds to a driver membrane protein and a second binding domain which binds to a target membrane protein, wherein the cell comprises a cell membrane, and the driver membrane protein and target membrane protein are associated with the cell membrane where the target membrane protein positions, and are internalized into a cell and degraded when the first binding domain of the dual binding molecule binds the driver membrane protein; as well as related methods and compositions.

Method of target membrane protein depletion

Growing community of inventors

Seongnam-si, South Korea

Christina Yi