Auckland Uniservices Limited

Christina Maree Buchanan

William Alexander Denny

Gordon William Rewcastle

Swarnalatha Akuratiya Gamage

Garth James Smith Cooper

Jack Urquhart Flanagan

Muriel Bonnet

Guo-Liang Lu

Stephen Michael Frazer Jamieson

Peter Robin Shepherd

Andrew James Marshall

Disclosed are tricyclic heterocyclic compounds having kinase inhibitory activity, pharmaceutical compositions and kits comprising the compounds, and use of the compounds in the treatment of or in medicaments for the treatment of various diseases and conditions. In particular, disclosed are tricyclic heterocyclic compounds of the formula (I) having CSF-1R (c-FMS kinase) inhibitory activity and their use in the treatment of various diseases and conditions, such as those mediated by CSF-1R, including proliferative or neoplastic diseases and conditions, including cancers, and bone, inflammatory, and autoimmune diseases and conditions.

Tricyclic heterocyclic derivatives and uses thereof

The inventions relate generally to vesiculin peptides and vesiculin peptide chains, and fragments, variants and derivatives thereof, related compositions and formulations and their preparation and use, nucleic acids encoding such vesiculin peptides and vesiculin peptide chains, and fragments, variants and derivatives thereof and related vectors and host cells, hybridomas and antibodies, and methods for the prevention and treatment of conditions, diseases and disorders that would be improved, eased, or lessened by the administration of a composition of the invention, including but not limited to glucose metabolism diseases.

Vesiculins

Growing community of inventors

Auckland, New Zealand

Christina Maree Buchanan