Siemens Aktiengesellschaft

Universität Des Saarlandes

Ares Genetics Gmbh

Christina Backes

Andreas Keller

Eckart Meese

Petra Leidinger

Andreas Kappel

Cord Friedrich Stähler

Daniel Sickert

Jan Kirsten

Susanne Schmolke

Cord Friedrich Stahler

Valentina Galata

Gabriel Rensen

The invention relates to methods for diagnosing Parkinson's Disease PAD) with miRNA markers. Towards the identification of biomarkers for diagnosis of PD, a comprehensive analysis of miRNA expression patterns was obtained. Significantly deregulated miRNAs were identified.

Diagnostic MiRNA markers for Parkinson's disease

The invention relates to novel miRNA markers useful for diagnosis or therapy of disease, in particular for neuronal disorders such as Alzheimer's Disease (AD).

MiRNAs as diagnostic markers

The invention relates to methods for diagnosing multiple sclerosis with miRNA markers. Diagnosis of multiple sclerosis (MS) can be challenging in patients with atypical presentations and during a first neurological deficit possibly related to inflammatory demyelination. Towards the identification of biomarkers for diagnosis of MS, a comprehensive analysis of miRNA expression patterns was obtained. Significantly deregulated miRNAs were identified, which have previously not been related to MS according to the microRNA disease database. These miRNAs could potentially serve as future diagnostic biomarkers for MS and help in diagnosis, monitoring disease activity, and evaluation of treatment responses in patients with MS.

Diagnostic miRNA profiles in multiple sclerosis

The invention relates to methods for diagnosing Alzheimer's Disease (AD) with miRNA markers. Diagnosis of AD Towards the identification of biomarkers for diagnosis of AD, a comprehensive analysis of miRNA expression patterns was obtained. Significantly deregulated miRNAs were identified.

Diagnostic miRNA markers for Alzheimer

Diagnostic miRNA markers for Parkinson disease

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Saarbrücken, Germany

Christina Backes