Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V.

Glatt Ingenieurtechnik Gmbh

Glatt Systemtechnik Gmbh

Christiane Wetzel

Volker Kirchhoff

Jörg Kubusch

Jessy Schönfelder

André Weidauer

Sebastian Ulbert

Ralf Kretzschmar

Olaf Roeder

Frank-Holm Rögner

Gaby Gotzmann

Reinhard Boeber

Frank-Holm Roegner

Henrik Flaske

Thomas Wegner

Wolfgang Prahl

Simona Walker

Olaf RÖDER

Reinhard Böber

A method may be provided for inactivating biologically active components in a liquid using low-energy electrons generated by an electron source, the electrons having an acceleration voltage of 25 keV to 300 keV. The method comprises the following steps: a) filling a vessel with a liquid volume; b) applying low-energy electrons to a first partial volume of the liquid filled into the vessel, wherein the first partial volume is a maximum of 10% of the liquid volume in the vessel; c) mixing the first partial volume of the liquid, applied with the low-energy electrons, to the second partial liquid volume in the vessel, which has not been applied with low-energy electrons; d) repeating steps b) and c) several times.

Method for inactivating biologically active components in a liquid

A method may be provided for stimulating the growth of a biomass, which is mixed with a liquid inside a bioreactor, by means of ionising radiation. The following method steps are used: a) exposing a first partial volume of the liquid in the bioreactor to ionising radiation, the first partial volume comprising at most 10% of the liquid volume in the bioreactor; b) mixing the first partial liquid volume, which has been exposed to ionising radiation, with the second partial liquid volume, which has not been exposed to ionising radiation, in the bioreactor; c) repeating method steps a) and b) multiple times, each partial volume of the liquid in the bioreactor being exposed to a total radiation dose of at most 50 Gy on statistical average.

Method for stimulating the growth of a biomass, contained in a liquid, inside a bioreactor

The invention relates to a method for inactivating viruses, characterized in that an immunogenic composition or vaccine comprising at least one virus is irradiated with electron beams, said immunogenic composition or vaccine comprising at least one virus (i) being liquid, in particular being a suspension and (ii) comprising at least one viral immunogen, wherein the antigen structure is preferably substantially retained.

Method for inactivating viruses using electron beams

Method and device for inactivating a microbiologically contaminated mass containing solid particles. The method includes mixing the mass containing solid particles with a gelatinizing agent, transporting the mixed mass of solid particles and gelatinizing agent through a shaping device structured so that the mixed mass, at least in one area, is shaped to form a lamellar volume with a layer thickness of between 1 mm and 3 mm, and impinging the formed lamellar volume of the mixed mass with accelerated electrons.

Method and device for inactivating a microbiologically contaminated mass containing solid particles with accelerated electrons

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Dresden, Germany

Christiane Wetzel