Laboratoires Fournier Sa

Laboratories Fournier S.a.

Christiane Legendre

Jean Louis Binet

Martine Barth

Pierre Dodey

Olivia Poupardin-Olivier

Benaïssa Boubia

Benaiessa Boubia

Indole compounds corresponding to the formula (I): as defined in the claims, pharmaceutically acceptable addition salts of such compounds, pharmaceutical compositions containing such compounds, the process for their preparation, and their use as pharmacologically active substances, especially in the treatment of hypertriglyceridemia, hyperlipidemia, hypercholesterolemia, diabetes, endothelial dysfunction, cardiovascular disease, inflammatory disease and neurodegeneration.

Method of treating conditions involving PPAR-receptors with indole compounds

Indole compounds, method of preparing them and uses thereof

A method of activating PPAR receptors in a subject, said method comprising administering to said subject an effective PPAR receptor activating amount of a pyrrolopyridine compound corresponding to formula (I): wherein R, R, R, R, R, X, Ar and n have defined meanings, or a pharmaceutically acceptable salt thereof, particularly as part of the treatment of a disorder or disease state selected from the group consisting of atherosclerosis, myocardial infarction, hypertension, and cerebral vascular disease.

Use of pyrrolopyridine compounds for activating PPAR receptors and treatment of conditions involving such receptors

Pyrrolopyridine compounds corresponding to formula (I): as defined in the claims, pharmaceutically acceptable salts thereof, the process for preparing such compounds, pharmaceutical compositions containing such compounds, and their use as pharmacologically active substances, especially in the treatment of hypertriglyceridemia, hyperlipidemia, hypercholesterolemia, diabetes, endothelial dysfunction, cardiovascular diseases, inflammatory diseases and neurodegenerative diseases.

Pyrrolopyridine compounds, method of making them and uses thereof

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Velard sur Ouche, France

Christiane Legendre