Roche Molecular Systems, Inc.

Roche Diagnostics International Ag

Roche Diagnostics Operations, Inc.

Roche Diabetes Care, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Christian Thalmann

Renato Belz

Simon Scheurer

Maximilian Ruhstorfer

Adnan Wahid William Aksoy

Martin Wyss

Rolf Knobel

Andreas Gisler

Robert Huesler

Reto Aeschlimann

Jürg Liniger

Hanspeter Stoller

Urs Knecht

Torsten Kraft

Lukas Dysli

Armin Bucher

Simon Scheuer

Thomas Huber

Reto Joho

Michael Weibel

Reto Aeschilmann

Veronika Schaerer

Veronika Trottmann

Veronika Schärer

Microwell plate assembly

Microwell plate

The present disclosure relates to an analytical system with at least three components: a multiwell plate on which the wells are included in an optically transparent area; a frame holding the multiwell plate close to its edge while permitting the plate a certain extent of freedom of movement; a baseplate to which the multiwell plate, but not the frame is firmly fixed via a docking mechanism, such that different expansion of plate and frame can be compensated. A second aspect described herein relates to a method of docking a corresponding multiwell plate held by a frame to a baseplate and subjecting the multiwell plate to a step of a biological or chemical assay within this arrangement.

Analytical system with accurate positioning of multiwell plates

Frame for a microwell plate assembly

Carrier for microwell plates

A positioning system for positioning a consumable rack in a diagnostic system is disclosed. The positioning system comprises a rack comprising an upper surface comprising holding positions and a receiving compartment comprising a rectangular chassis comprising front, rear, and two lateral sides. The receiving compartment comprises a holding structure coupled to the chassis to move between first and second positions. The rack comprises sidewalls. At least three sidewalls have a center alignment element. The chassis comprises three chassis alignment elements on the rear and two lateral sides. The holding structure comprises a corner push element between the chassis front and lateral sides to push against a side edge of the rack between two sidewalls when the holding structure is moved from the first position towards the second position forcing the three alignment elements against a chassis alignment element and laterally holding the rack in position by the chassis alignment elements.

Rack positioning system

The present invention relates to an automated analytical system and an automated method for separating and detecting an analyte, as well as an automated analytical instrument.

System for separating and detecting an analyte

A method is provided for disposing of a liquid within an automated analytical system for processing a fluid biological sample, wherein a contamination prevention shield including channels for pipets or pipet tips is reversibly docked to a container for liquid waste in order to reduce the risk of cross-contamination. A tip rack assembly is provided for processing a fluid sample, the assembly including a rack for pipet tips and the contamination prevention shield. An analytical system is provided using the tip rack assembly, wherein cross-contamination is avoided.

Method for prevention of contamination during disposing of liquid by pipet array

An automated method of isolating and analyzing an analyte using a form-locking gripping mechanism. An analytical system comprising consumables and a handler, wherein the handler and consumable interact with a form-locking gripping mechanism are also included.

Form-locking gripping system

A cassette is described which can hold at least two multiwell plates. The cassette comprising the multiwell plates can be loaded into a stacker of an automated analytical apparatus. While the stacker holds down the cassette, a lift pushes the multiwell plates upwards to make them accessible to a handler which can engage and transport the multiwell plates to a plate holder in the working area of the analytical apparatus.

Cassette with multiwell plates

An arrangement for introducing a liquid into the body of a patient or for withdrawing a liquid from the body of a patient, including a first structural part carrying a cannula for positioning in the body of the patient, and a second structural part with a connection port for detachably coupling a conduit for supplying or withdrawing a liquid, wherein the first and second structural parts are connected, can be rotated relative to each another and in relative rotational positions form a channel for introducing a liquid from the conduit to the cannula or for withdrawing a liquid from the cannula to the conduit, and whereby movement of the conduit for coupling and uncoupling is transverse to the longitudinal axis of the cannula.

Rotatable infusion set

Growing community of inventors

Kehrsiten, Switzerland

Christian Thalmann