Leica Microsystems Cms Gmbh

Christian Schulz

Christian Schumann

Tobias Bauer

Arnold Mueller-Rentz

Andreas Lotter

Ralf Krueger

Benjamin Deissler

Alexander Weiss

Martin Kubek

Sebastian Hitzler

Klaus Hermanns

Frank Eisenkraemer

Ralf Krüger

Cornell Gonschior

Arnold Müller-Rentz

Ralf KRÜGER

Alexander Weiß

An optical system for a microscope for imaging an object includes: a telescope system having an optical correction unit, which is adjustable in order to correct a spherical imaging aberration, and having a zoom optical unit, which is adjustable in order to adapt a magnification of the telescope system to a ratio of two refractive indices, one of which is assigned to an object side and an other of which is assigned to an image side, within a predetermined magnification range. The telescope system is telecentric over an entire magnification range both with respect to the object side and with respect to the image side by the zoom optical unit contained in the telescope system.

Optical system for a microscope

An optical imaging device for a microscope includes an objective and an optical system configured to interact with the objective for optically imaging an object selectively in a first operating mode and a second operating mode. The optical system includes a first optical subsystem associated with the first operating mode, and a second optical subsystem associated with the second operating mode. The first optical subsystem is configured to form a first image of the object with a first magnification. The second optical subsystem is configured to form a second image of the object with a second magnification that is less than the first magnification. The second optical subsystem includes an optical module insertable into the optical path for selecting the second operating mode. The optical module includes a lens element with a positive refractive power.

Device and method for imaging an object

A microscope includes: an optical system including an immersion objective for an immersion medium of a predetermined refractive index; an aperture stop; and a processor for setting an immersion-free imaging mode in which the optical system is operated without immersion medium. The processor controls the aperture stop in the immersion-free imaging mode to set a numerical aperture of the immersion objective to a reduced value which is lower than a nominal value of the numerical aperture, the numerical aperture being equal to the nominal value when the optical system is operated using the immersion medium without reducing the numerical aperture by the aperture stop. The processor controls the optical system in accordance with the reduced value of the numerical aperture in the immersion-free imaging mode to generate at least one image representing the overview image of the sample.

Microscope and method for generating an overview image of a sample

An optical assembly includes a lens unit capable of being moved along an optical axis of the optical assembly. The lens unit includes a lens mount for holding at least one lens. The optical assembly further includes a sleeve for receiving the lens mount. The lens mount is in sliding contact with and movable in relation to the sleeve as the lens unit is moved along the optical axis. The lens mount is formed of or comprises at its outer surface a self-lubricating material, and/or the sleeve is formed of or comprises at its inner surface a self-lubricating material.

Optical assembly having a movable lens unit

The invention relates to a correction objective (), comprising a first lens group () of positive optical power, a second lens group () of positive optical power, a third lens group () of negative optical power, and a fourth lens group () of positive optical power, which are arranged in this order from the object side, the second lens group () being movable along the optical axis (O) in such a way that the sum of the distance (V) between the second lens group () and the first lens group () and the distance (V) between the second lens group () and the third lens group () is constant. The image scale of the second lens group () lies in a range of &#x2212;0.9 to &#x2212;1.1.

Correction objective for a microscope

A microscope system includes a detection unit having a color beam splitter arrangement with three beam splitter prisms, each having first, second and third prism surfaces. The first prism surfaces face in the same direction and are oriented parallel to one another at a right angle to an optical axis. The first and second prism surfaces are oriented in each case at acute angles to one another. The second and third prism surfaces are oriented in each case at right or obtuse angles to one another. The third and first prism surfaces are oriented in each case at acute angles to one another. A prismatic compensation element having first and second prism surfaces is assigned to each prism. The second prism surface of each of the compensation elements is arranged in a common plane with or parallel to the second prism surface of the respectively assigned prism.

Microscope system and method for microscopic imaging

An immersion objective lens for a microscope includes a first lens group having positive refractive power, a second lens group having positive refractive power, a third lens group having negative refractive power and a fourth lens group having positive refractive power disposed in this sequence from the object side. The second lens group is moveable along an optical axis so as to achieve a corrective effect with respect to a spherical aberration, such that a sum of a distance between the second lens group and the first lens group and of a distance between the second lens group and the third lens group is constant. The corrective effect of the second lens group is predetermined such that the spherical aberration is minimized for a light incidence that corresponds to a mean numerical aperture that lies between zero and a nominal aperture of the immersion objective lens.

Immersion objective lens for a microscope

A microscope includes at least one correction unit arranged in a beam path for correcting a variable spherical aberration. The correction unit has at least one optical correction element that is arranged in a convergent or divergent area of the beam path such that the optical correction element is movable along an optical axis. The at least one optical correction element has at least one correction surface. A part of the at least one correction surface through which the convergent or divergent area of the beam path passes forms a correction-effective surface section whose radial extension crosswise to the optical axis is adjustable by moving the correction element along the optical axis.

Microscope having a correction unit for correcting a variable spherical aberration

An illumination device for an optical device, a microscope or a macroscope includes a first illumination source configured to emit light which is directed via an illumination beam path onto an object to be illuminated that is arranged in an object plane. At least one second illumination source is positionable in the illumination beam path, and is transparent or semitransparent as well as self-luminous. The at least one second illumination source is configured to allow light emitted from the first illumination source to pass through at least in part. The object plane having the object to be illuminated is configured to be illuminated both by the first and by the at least one second illumination source.

Illumination device

A microscope immersion objective having a numerical aperture of NA&#x3e;1.36 includes a front lens group. The front lens group has a first, object-side optical element having a plane parallel plate and a second optical element having a hyper-hemisphere. The plane parallel plate is wrung together with a planar side of the hyper-hemisphere.

Immersion objective for microscopes and use thereof

The present invention relates to a microscope illumination system for switching between a first, confocal and a second, non-confocal microscope illumination mode, the system having an illumination unit that, in order to provide the first illumination mode, includes an illumination source for generating an illumination beam propagating parallel to the optical axis; a scanning mirror for deflecting the illumination beam perpendicular to the optical axis; and a scanning eyepiece and a downstream scanning tube lens for imaging the scanning mirror into the back focal plane of a microscope objective and for expanding the illumination beam, the objective focusing the illumination beam onto a specimen to be examined. In order to provide the second illumination mode, the system has a focusing lens inserted into the path of the illumination beam in such a way that the illumination beam is focused into the back focal plane of the microscope objective.

Microscope having switchable illumination modes and method of operating the same

The present invention relates to a polarization interference microscope () for imaging objects (). The polarization interference microscope () comprises a light source (), an illumination beam path (), an imaging beam path () and an objective (). The illumination beam path () extends from the light source () to the object (). The imaging beam path () extends from the object () to a detector or a tube (). At least one polarization means () is provided in the illumination beam path () and/or in the imaging beam path (), by which at least one polarization means the light of the respective beam path () can be converted into a predeterminable polarization state. An analyzer means () is provided in the imaging beam path (). A birefringent component is provided between the polarization means () and the analyzer means (), by which birefringent component the light polarized by the polarization means () can be divided into two partial beams () having different polarization directions. The component can produce a splitting between the two partial beams (). The present invention furthermore relates to a retrofit kit for a conventional microscope and for a conventional polarization interference microscope, respectively, and a method for imaging objects. In order to enable variable contrasting of the interference contrast, the polarization interference microscope () according to the invention is characterized by the fact that the component has a liquid crystal element () formed in such a way that the value of the splitting between the two partial beams () is settable in a variable manner thereby.

Polarization interference microscope

A microscope () is disclosed, having a revolving nosepiece () on which are mounted multiple objectives. The objectives () comprise multiple components). A light-intensity-reducing layer () is applied onto at least one component of an objective. The light-intensity-reducing layer () is configured in such a way that for each objective introduced into the illumination beam path, the brightness behind it is of the same magnitude.

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Solms, Germany

Christian Schulz