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Rohm Gmbh

Christian Rietzel

Karl-Dieter Voelger

Klaus Lehmann

Ernst Mutschler

Heinrich Knauf

Pteridine compounds, useful as diuretics, of the formula ##STR1## wherein R.sub.1 and R.sub.2 taken alone are, independently of each other, hydrogen, alkyl having from 1 to 6 carbon atoms, or benzyl, or wherein R.sub.1 and R.sub.2, taken together with the nitrogen atom to which they are bound, form a five- or six-membered heterocyclic ring system or such a ring containing one or two further hetero atoms, or wherein R.sub.1 and R.sub.2 together with the nitrogen are ##STR2##

Pteridine compounds

A pharmaceutical composition for inducing diuresis, which composition comprises a diuretically-effective amount of the sulfuric acid half ester of 2,4,7-triamino-6-p-hydroxyphenyl pteridine or of a physiologically tolerable salt thereof in combination with a pharmaceutical carrier.

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Heidelberg, Germany

Christian Rietzel