Entratympanic, LLC

Harvard College

Christian Pfeffer

George B Kenney

Lev Rosenblum

Lukas Lichtensteiger

A device insertable in the ear canal for substance delivery to and/or extraction from the tympanic cavity is described that includes a stationary body having a distal surface, a proximal surface; a movable body having a distal surface and a proximal surface, disposed within the stationary body and free to move relative to the stationary body in response to a pressure difference created in the ear canal; and at least one piercing element having a distal end and a proximal end, disposed in the movable body.

Device and method for delivering medicine into the tympanic cavity, with sliding assist

A device for substance delivery to and/or extraction from the tympanic cavity, comprising: a stationary body having a distal surface, a proximal surface; a movable body having a distal surface and a proximal surface, disposed within the stationary body and free to move relative to the stationary body; at least one piercing element having a distal end and a proximal end, disposed in the movable body; and a means for moving the movable body relative to the stationary body.

Device and method for delivering medicine into the tympanic cavity,with sliding assist

In a method for producing a free-standing solid state layer, a solid state material is provided having at least one surface available for layer formation thereon and a layer of polymer is formed on the available surface. The solid state material and polymer layer are then exposed to a change in local temperature from a first temperature that is no greater than about 300&#xb0; C. to a second temperature below about room temperature to cause the solid state material to fracture along a plane at a depth in the material, to produce at least one free-standing solid state layer from the solid state material.

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Somerville, MA, United States of America

Christian Pfeffer