Johannes Gutenberg-universitatis

Johannes Gutenberg-Universität Mainz

Christian Peifer

Gerd Dannhardt

Stanislav Plutizki

Jan-Peter Kramb

The present invention relates to a compound of formula (I) wherein Ris H, C-C-alkyl, phenyl-C-C-alkyl or phenyl, Ris a phenyl group which is substituted with 2 or 3 C-C-alkoxy groups and Ris indolyl or azaindolyl which may carry one or two substituents independently selected from C-C-alkyl, C-C-alkoxy, phenyl, OH, halogen, NH, C-C-alkylamino, di-C-C-alkylamino, heteroaryl with 5 or 6 ring atoms containing 1 or 2 heteroatoms which are independently selected from O, N, and S and heterocyclyl with 5 or 6 ring atoms containing 1 or 2 heteroatoms which are independently selected from O, N, and S and the physiologically acceptable salts thereof as well as the physiologically acceptable solvates of the compounds of formula 1 and of the salts thereof. The compounds of formula (I) are suitable for controlling angiogenesis. 

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Christian Peifer