Evonik Degussa Gmbh

Degussa Aktiengesellschaft

Hte Aktiengesellschaft the High Throughput Experimentation Company

Christian Lettmann

Gerda Grund

Guido Stochniol

Matthias Orschel

Guido Streukens

Thomas Haas

Stephan Kohlstruk

Bernd Jaeger

Norbert Finke

Cord Knoop

Juergen Lippe

Emmanouil Spyrou

Willi Hofen

Uwe Dingerdissen

Armin Matthias Rix

Thomas Tacke

Monika Berweiler

Martina Ortelt

Manfred Kreczinski

Axel Hengstermann

Jan Christoph Pfeffer

Harald Schmidt

Daniel Ostgard

Robert Jansen

Joerg-Joachim Nitz

Jens Klein

Markus Schwarz

Jorg Sauer

Sven Schneider

Martin Maier

Klaus Stadtmueller

Michael Volland

Wilhelm F Maier

Joerg Lotz

Roger Sheldon

Michiel Janssen

Michael Rimbach

Markus Galle

Norbert Richter

Hans Werner Schmidt

Rolf Hirsch

Michael D Hinton

Ranier Lomoelder

Jan Pfeffer

Andreas Luecke

The invention relates to an improved process for preparing 3-aminomethyl-3,5,5-trimethylcyclohexylamine, referred to hereinafter as isophoronediamine or, in abbreviated form, IPDA, by: I. preparation of isophorone by catalyzed aldol condensations with acetone as reactant; II. reaction of isophorone with HCN to form isophoronenitrile (IPN, 3-cyano-3,5,5-trimethylcyclohexanone); III. catalytic hydrogenation and/or catalytic reductive amination (also referred to as aminative hydrogenation) of 3-cyano-3,5,5-trimethylcyclohexanone, hereinafter called isophoronenitrile or, in abbreviated form, IPN, to give the isophoronediamine.

Process for preparing 3-aminomethyl-3,5,5-trimethylcyclohexylamine

Method for preparing diamino-dianhydro-dideoxyhexitols, particularly 2,5-diamino-1,4:3,6-dianhydro-2,5-dideoxy-D-hexitol. The invention related to a method for preparing diamino-dianhydro-dideoxyhexitols, particularly preferably 2,5-diamino-1,4:3,6-dianhydro-2,5-dideoxy-D-hexitol.

Method for preparing diamino-dianhydro-dideoxyhexitols, particularly preferably 2,5-diamino-1,4:3,6-dianhydro-2,5-dideoxy-D-hexitol

The invention relates to an improved process for preparing 3-aminomethyl-3,5,5-trimethylcyclohexylamine, referred to hereinafter as isophoronediamine or IPDA for short, by means of catalytic hydrogenation and/or catalytic reductive amination (also referred to as aminating hydrogenation) of 3-cyano-3,5,5-trimethylcyclohexanone, also called isophoronenitrile or IPN for short hereinafter.

Low chlorine, multi-staged method for producing cycloaliphatic diisocyanates. The invention relates to a multi-staged method for the continuous low-chlorine production of cycloaliphatic diisocyanates, comprising the synthesis of diaminodipheynl alkanes, the hydration thereof into the corresponding cycloaliphatic diamines and the subsequent conversion of cycloaliphatic diamines to the corresponding cycloalkylene biscarbamates and the thermal cleaving of the latter into the cycloaliphatic diisocyanates and alcohol.

Low chlorine, multi-staged method for producing cycloaliphatic disocyanates

The invention relates to a method for producing 2,6-dioxabicyclo-(3.3.0)-octane-4,8-dione (I), comprising the oxidation of dianhydrohexitols (II-IV), or of corresponding hydroxy ketones, with an oxygen-containing gas in the presence of a catalyst composition, the reaction proceeding without the addition of halogen sources.

Method for producing 2,6-dioxabicyclo-(3.3.0)-octane-4,8-dione

The invention relates to an improved process for preparing trimethylhexamethylenediamine, hereinafter referred to as TMD for short, by hydrogenation of trimethylhexamethylenedinitrile, hereinafter referred to as TMN for short, in the presence of a shaped hydrogenation catalyst of the Raney type.

Method for production of trimethylhexamethylenediamine

The invention relates to a process for increasing the selectivity of the hydrogenation of 4,4'-diaminodiphenylmethane (4,4&#x2032;-MDA) to diaminodicyclohexylmethane (4,4&#x2032;-HMDA) by catalytic hydrogenation of a mixture containing 4,4&#x2032;-MDA as the main component and its mono-N-methyl derivative as a secondary component. According to the invention, the hydrogenation is terminated before a conversion of 4,4&#x2032;-MDA to 4,4&#x2032;-HMDA of 99% is achieved. Under these conditions, a substantially smaller proportion of the N-methyl-4,4&#x2032;-MDA is hydrogenated to N-methyl-4,4-HMDA.

Process for increasing the selectivity of the hydrogenation of 4,4'-diaminodiphenylmethane to 4,4&#x2032;-diaminodicyclohexylmethane in the presence of an N-alkyl-4,4&#x2032;-diaminodiphenylmethane

The invention relates to an automated method for carrying out reactions with high spatial resolution on libraries of different materials and for analysis of the products obtained using a simple robot system and an analyzer, for example a mass spectrometer.

Automated method for examining catalytic and spectroscopic properties of the components of combinatorial libraries

The invention relates to a method for synthesis of aliphatic isocyanates from aromatic isocyanates in substantially 3 stages. In particular, the invention relates to a method for synthesis of bis{4-isocyanatocyclohexyl}methane (HMDI) from bis{4-isocyanatophenyl}methane (MDI). More especially, the invention relates to a method for synthesis of HMDI with a trans-trans isomer content of &#x3c;30%, preferably of &#x3c;20%, particularly preferably of 5 to 15%.

Method for synthesis of aliphatic isocyanates from aromatic isocyanates

The invention relates to a method for hydrogenation of aromatic urethanes, which contain one or more aromatic rings and one or more urethane groups bonded directly and/or indirectly to one aromatic ring or to different aromatic rings, using hydrogen in the presence of a supported catalyst, which contains ruthenium as active metal. The catalyst support of the catalyst to be used according to the invention has a BET surface ranging from larger than 30 m /g to smaller than 70 m /g and more than 50% of the pore volume of the catalyst support is represented by macropores with a pore diameter of larger than 50 nm and less than 50% is represented by mesopores with a pore diameter of 2 to 50 nm. The method is suitable in particular for hydrogenation of dibutyl 4,4&prime;-methylenedicarbanilate to dibutyl 4,4&prime;-methylenedicyclohexylcarbamate with a trans-trans isomer content of <30%, preferably of <20%, particularly preferably of 5 to 15%.

Method for hydrogenation of aromatic urethanes in the presence of a supported ruthenium catalyst

Process for the preparation of isophorone diamine from isophorone nitrile, isophorone nitrilimine or mixtures containing isophorone nitrile and/or isophorone nitrilimine by hydrogenation through to amine in the presence of at least ammonia, hydrogen and a formed Raney hydrogenation catalyst based on cobalt, nickel, copper and/or iron, wherein the Raney catalyst is present in the form of hollow bodies.

Process for the preparation of 3-aminomethyl-3,5,5-trimethylcyclohexylamine

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Coesfeld, Germany

Christian Lettmann