Universitaet Zu Luebeck

Christian Kaethner

Thorsten Manuel Buzug

Gael Bringout

Mandy Gruettner

Matthias Weber

The invention relates to a method and an MPIS scanner for tomographic imaging of an object with magnetic particles distributed in the interior of the object, comprising the steps of generating a selection magnetic field with a predetermined magnetic field gradient in at least one field-free point (FFP) in a predetermined scanning plane, generating a time-dependent, periodic excitation magnetic field with a predetermined maximum frequency, repeatedly displacing the at least one FFP along a predetermined closed trajectory with a predetermined repetition time in the scanning plane, moving the object through the scanning plane along a predetermined advance direction with a predetermined advance speed, detecting the change in the magnetization state of the magnetic particles at the points in the object interior through which the at least one FFP passes, reconstructing the local particle concentrations at the points through which the at least one FFP passes in respect of an object coordinate system, interpolating the reconstructed particle concentration to the points in the object interior not passed through by at least one FFP, generating a display of the particle concentration distribution in the object interior, characterized by interpolating the particle concentrations reconstructed at path section end points of path sections along the advance direction to path section intermediate points taking into account the advance speed.

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Luebeck, Germany

Christian Kaethner