Pfizer Corporation

Warner-lambert Company

Christian J Mularski

Roger B Ruggeri

Ronald Thure Wester

Ernest S Hamanaka

Angel Guzman-Perez

Michael P Deninno

Michael Paul DeNinno

Ronald T Webster

NHE-1 inhibitors, methods of using such NHE-1 inhibitors and pharmaceutical compositions containing such NHE-1 inhibitors. The NHE-1 inhibitors are useful for the reduction of tissue damage resulting from tissue ischemia.

N-[(substituted five-membered di-or triaza diunsaturated ring) carbonyl] guanidine derivatives for the treatment of ischemia

N-&lsqb;(substituted five-membered di- or triaza diunsaturated ring)carbonyl&rsqb; guanidine derivatives for the treatment of ischemia

Cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.

4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines

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Chester, CT, United States of America

Christian J Mularski