Sanofi

Sanofi-aventis

Sanofi-synthelabo

Christian Hoff

Bruno Franc

Chenkou Wei

Olivier Monnier

San Kiang

Mark D Lindrud

Raphael Sole

Jean-Claude Rovera

Pierre Jean Grossi

Eric Garcia

Raphaël Sole

The invention relates to a method for preparing 1,6:2,3-dianhydro-&#xe2;-D-mannopyranose and is characterized in that it includes a step of cyclizing the compound C, where R is an alykyl group and R' is an activating agent, in an alcohol/alcoholate mixture under anhydrous conditions. 

Method for preparing 1,6:2,3-dianhydro-&#x3b2;-D-mannopyranose

The invention relates to a novel crystalline form of irbesartan to pharmaceutical compositions containing it, to processes for preparing it, and to a method for treating cardiovascular diseases utilizing it.

Form of irbesartan, processes for obtaining the said and pharmaceutical compositions containing it

The invention relates to a novel crystalline form of irbesartan, to pharmaceutical compositions containing it, to processes for preparing it, and to a method for treating cardiovascular diseases utilizing it.

Form of irbesartan, methods for obtaining said form and pharmaceutical compositions containing same

The invention relates to a process for obtaining procyanidol oligomers according to which: an appropriate plant is treated by means of an extractive mixture composed of water, of a water-miscible organic solvent capable of dissolving the procyanidol oligomers and of sodium chloride, the crude mixture of procyanidol oligomers obtained is purified by removal of the extractive mixture and extraction of the residue, the extractive mixture optionally being recycled in the stage of treatment of the plant, the procyanidol oligomers are recovered in a pure form by precipitation.

Process for obtaining procyanidol oligomers from plants by extractions

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Saint Laurent des Arbres, France

Christian Hoff