L'oreal

Societe L'oreal Sa

Christian Colin

Quang L N'Guyen

Alex M Junino

Quang Lan Nguyen

Jean-Francedillaois Nadaud

Patricia Marchi-Lemann

Catherine Loufrani

Albert Lindenbaum

A method of preventing damage caused to healthy skin, hair or mucous membranes by free radicals, includes applying to the healthy skin, hair or mucous membrane a composition containing at least one product having a peroxidase activity capable of reducing organic peroxides and at least one antioxidant capable of neutralizing singlet oxygen, the composition being free of peroxide. The product having a peroxidase activity is present in an amount of from 0.005 to 5.0% by weight, and the antioxidant is present in an amount of from 0.005 to 3.0% by weight, with a weight ratio of the product having a peroxidase activity to the antioxidant of from 0.001 to 0.3. The product having a peroxidase activity capable of reducing organic peroxides is lactoperoxidase, and the antioxidant is selected from quinolines, polyphenols, and carotenoids.

Cosmetic or pharmaceutical composition comprising, in combination, a peroxidase and an anti-singlet oxygen agent

Topically applicable dermocosmetic compositions for combating the clinical signs of skin aging and/or for improving the appearance of the skin, the scalp or the hair, comprise an anti-free-radical effective amount of at least one novel melatonin derivative having the structural formula (I): ##STR1## in which R.sub.1 is a lower alkyl radical, R.sub.2 is a hydrogen atom or a lower alkyl radical, and R.sub.3 is a hydrogen atom or a lower acyl radical, with the proviso that the hydroxyl radical is in the 4-, 6- or 7-position on the indole ring system, or a physiologically acceptable salt, solvate or bioprecursor/prodrug thereof, formulated into a topically applicable, cosmetically/dermatologically acceptable vehicle, carrier or diluent therefor.

Melatonin derivatives and anti-free-radical dermocosmetics comprised

Cosmetic, hygienic or dermopharmaceutical composition characterized in that it comprises, in combination, at least one superoxide-dismutase and at least one melanin pigment. In such a composition the melanin pigment reinforces synergistically the action of the SOD against free radicals. Application especially to combating cell aging and to the protection of the skin, of the hair and of the mucosa against the harmful and unaesthetic effects caused by free radicals.

Cosmetic composition containing, in combination, a superoxide-dismutase

Cosmetic composition, characterized in that it contains titanium dioxide nanopigments coated with at least aluminium derivatives in a cosmetically acceptable, fairly nonpolar medium having a conductivity of less than 100 .mu.Siemens and containing at least one fatty phase.

Cosmetic composition which prevents or attenuates the photo-reactivity

The invention relates to a cosmetic and/or dermatological composition comprising at least one superoxide dismutase and at least one porphyrin. In a composition of this kind the porphyrin synergically reinforces the anti-free radical action of the superoxide dismutase. The composition is used in particular to combat cell ageing and/or for the protection of the skin, hair and/or mucosae against the harmful and/or unaesthetic effects caused by oxygen-containing free radicals.

Cosmetic composition containing a superoxide dismutase and a porphyrin

A process for topical treatment of cutaneous ageing involves applying to skin a cosmetic or dermatological composition containing, as an active ingredient, a glutathione alkyl ester. The glutathione alkyl ester corresponds to the formula: ##STR1## in which R represents an alkyl radical having from 1 to 10 carbon atoms.

Growing community of inventors

Paris, France

Christian Colin