Calhoun Vision, Inc.

Rxsight, Inc.

Other

University of California

California Institute of Technology

Christian A Sandstedt

Robert H Grubbs

Jagdish M Jethmalani

Julia A Kornfield

Daniel M Schwartz

Ben C Platt

Pablo Artal

Matt Haller

Ilya Goldshleger

John Kondis

Eloy Angel Villegas

Shiao H Chang

Robert E Maloney

James A Ebel

Eric A Pape

Eloy Angel

A light adjustable lens illumination system comprises an illumination source, for generating a light beam; a light delivery system, for projecting the light beam onto a Light Adjustable Lens (LAL), implanted into an eye, wherein a fraction of the light beam propagates past the LAL to a retina of the eye; and a protective beam-shaper, for shaping the light beam to have an intensity pattern with a relative central intensity reduction that varies along an axis; wherein the relative central intensity reduction at the retina is greater than the relative central intensity reduction at a LAL plane.

Light-adjustable lens illumination system with fovea protection

A Light Adjustable Lens (LAL) comprises a central region, centered on a central axis, having a position-dependent central optical power, and a peripheral annulus, centered on an annulus axis and surrounding the central region, having a position-dependent peripheral optical power; wherein the central optical power is at least 0.5 diopters different from an average of the peripheral optical power, and the central axis is laterally shifted relative to the annulus axis. A method of adjusting the LAL comprises implanting a LAL; applying a first illumination to the LAL with a first illumination pattern to induce a position-dependent peripheral optical power in at least a peripheral annulus, centered on an annulus axis; determining a central region and a corresponding central axis of the LAL; and applying a second illumination to the LAL with a second illumination pattern to induce a position-dependent central optical power in the central region of the LAL.

Blended extended depth of focus light adjustable lens with laterally offset axes

Method of adjusting a blended extended depth of focus light adjustable lens with laterally offset axes

In general, the present invention relates to optical elements, which can be modified post-manufacture such that different versions of the element will have different optical properties. In particular, the present invention relates to lenses, such as intraocular lenses, which can be converted into aspheric lenses post-fabrication. Also, the present invention relates to a method for forming aspheric lenses post-fabrication.

Using the light adjustable lens (LAL) to increase the depth of focus by inducing targeted amounts of asphericity

A color-apodized intraocular lens includes a lens center, with a center-transmittance to transmit an incident light; a lens annul us, surrounding the lens center, configured to selectively attenuate the incident light according to a radius- and wavelength-dependent annulus-transmittance, wherein the annulus-transmittance is less than the center-transmittance, in a short wavelength spectral range; and haptics, extending from the lens annulus. A method of making a color-apodized intraocular lens includes creating an intraocular lens mold using a base-polymer, the intraocular lens having a lens center, with a center-transmittance to transmit an incident light; a lens annulus, surrounding the lens center, configured to selectively attenuate the incident light according to a radius and wavelength-dependent annulus-transmittance, wherein the annulus-transmittance is less than the center-transmittance in a short wavelength spectral range; forming haptics, extending from the lens annulus; and applying a stimulus to the intraocular lens mold to form the color-apodized intraocular lens.

Depth of focus and visual acuity using colorized apodization of intra-ocular lenses

A method for adjusting a light adjustable lens in an optical system includes providing a light adjustable lens in an optical system; providing an ultraviolet light source to generate an ultraviolet light; and irradiating the generated ultraviolet light with a light delivery system onto the light adjustable lens with a center wavelength and with a spatial irradiance profile to change a dioptric power of the light adjustable lens by changing a refraction of the light adjustable lens in a refraction-change zone, thereby causing a wavefront sag, defined as half of a product of the change of the dioptric power and the square of a radius of the refraction-change zone, to be within 28% of its maximum over an ultraviolet spectrum.

Method for modifying power of light adjustable lens

A method for adjusting a light adjustable lens in an optical system includes providing a light adjustable lens in an optical system; providing an ultraviolet light source to generate an ultraviolet light; and irradiating the generated ultraviolet light with a light delivery system onto the light adjustable lens with a center wavelength and with a spatial irradiance profile to change a dioptric power of the light adjustable lens by changing a refraction of the light adjustable lens in a refraction-change zone, thereby causing a wavefront sag, defined as half of a product of the change of the dioptric power and the square of a radius of the refraction-change zone, to be within 10% of its maximum over an ultraviolet spectrum.

The invention relates to novel intraocular lenses. The lenses are capable of post-operative adjustment of their optical properties, including conversion from single focal lenses to multifocal lenses.

Light adjustable multifocal lenses

The present invention relates to lenses that are capable of post-fabrication power modifications. In general, the inventive lenses comprise (i) a first polymer matrix and (ii) a refraction modulating composition that is capable of stimulus-induced polymerization dispersed therein. When at least a portion of the lens is exposed to an appropriate stimulus, the refraction modulating composition forms a second polymer matrix. The amount and location of the second polymer matrix may modify a lens characteristic such as lens power by changing its refractive index and/or by altering its shape. The inventive lenses have a number of applications in the electronics and medical fields as data storage means and as medical lenses, particularly intraocular lenses, respectively.

Lenses capable of post-fabrication power modification

A method of correcting aberrations in an optical system by applying a light adjustable aberration conjugator layer to a component of the system, determining the nature of the aberration, applying radiation to the conjugator layer such as to change the refraction and/or shape of the conjugator layer to compensate for the aberration, and locking in the desired optical property.

Light adjustable aberration conjugator

The invention relates to a method of customizing lenses using an external stimulus such as light. Fine-tuning of the lens to match the precise optical requirements using the same lens is also possible. The lenses are self-contained and do not require the addition or removal of significant portions of the lens to achieve customization.

Growing community of inventors

Pasadena, CA, United States of America

Christian A Sandstedt