Mycartis N.v.

Tibotec Bvba

Biocartis S.a.

Protea Biopharma N.v.

Christiaan Hubert Simon Roelant

Joseph Demeester

Rudi Wilfried Jan Pauwels

Stefaan Cornelis De Smedt

Stefaan De Smedt

Kevin Braeckmans

Koenraad Lodewijk August Van Acker

Kenny Leo De Meirleir

Inge Dierynck

Jan Octaaf Antoon De Kerpel

Werner René Irène De Beukeleer

Marc Jan René Leblans

Emmanuel Marie Paul Ernest Gustin

Encoded microcarriers, and more specifically microcarriers having codes written on them. Methods for writing the codes on the microcarriers, methods of reading the codes, and methods of using the encoded microcarriers. A preferred method of encoding the microcarriers involves exposing microcarriers containing a bleachable substance to a high spatial resolution light source to bleach the codes on the microcarriers. The encoded microcarriers may be used, for example, as support materials in chemical and biological assays and syntheses.

Encoding of microcarriers

The present invention relates to a method for the manipulation for an identification purpose of a microcarrier comprising the steps of: (a) an identification purpose step of the microcarrier; and (b) a positioning and orientation step prior to or during the identification purpose step, wherein the identification purpose step is a detection step for the detection of an encoded microcarrier having an anisotropy in its shape. The invention further relates to an apparatus for the manipulation for identification purposes of a microcarrier comprising means for identification purposes such as a microscope and means for the positioning and orientation of the microcarriers.

Method and device for the manipulation of microcarriers for an identification purpose

A method for dispensing a volume of fluids from a reservoir, through a fluid outlet in fluid communication with said reservoir, into each well of at least a series of wells, whereby the fluid is dispensed into said series of wells at a continuous uninterrupted flow. A micro titer plate constructed from a hydrophobic and more in particular from a plastic material containing a plurality of series of wells and to an apparatus able to perform the above method.

Method and apparatus for dispensing a liquid into a series of wells

The present invention is directed to reporter molecules and tags that may be used to monitor a target substance in a biological system. More particularly, the present invention relates to the use of an apo metal binding protein as a reporter molecule or tag. An apo metal binding protein may be bound to a protein or tissue or introduced into a cell. The invention also relates to methods of utilizing the apo metal binding protein for detecting a cell expressing a protein of interest, localizing a protein in a cell, and designing a therapeutic agent for treating a disease or infection.

Method of monitoring a biological system by labeling with an apo metal binding protein

Growing community of inventors

Leuven, Belgium

Christiaan Hubert Simon Roelant