University of Rochester

Lucid, Inc.

Caliber Imaging and Diagnostics, Inc.

Christi Alessi Fox

Jay M Eastman

Allison L Cramb

Aleksandar Sekulic

David N Herrmann

David L Swanson

Allison L Reece

Allison L Schneider

Allison L Herschell

David Hermann

Neil Boger

A system is provided having a guide member with features, such as grid and axes, which spatially correlate to tissue with a lesion adjacent the guide member, and a template device upon the tissue aligned with the features having a first aperture over the guide member, and a second aperture over the tissue with the lesion. A microscope captures one or more images of the tissue via the second aperture at one or more locations each spatially correlated with a location selected or being mapped along the guide member in the first aperture. Prior to imaging and template device placement, marks are recorded along the guide member when, as part of a tracing sheet, it is positioned in a folded state over the lesion. When returned to an unfolded state, the guide member once removed from the tracing guide sheet is positioned for use with the template device and microscope.

System and method for mapping the locations of captured confocal images of a lesion in skin tissue

Meissner's Corpuscles (MCs) are touch-pressure sensation receptors in glabrous skin. They are imaged by reflectance confocal microscopy to provide a non-invasive, in vivo quantification of their density or size to allow screening for, diagnosis or monitoring of sensory neuropathy and other peripheral nervous system disorders related to diabetes, HIV, or other conditions.

Non-invasive in-vivo imaging of mechanoreceptors in skin using confocal microscopy

Growing community of inventors

Rochester, NY, United States of America

Christi Alessi Fox