Orexo Ab

Diabact Ab

Sensidos Ab

Neopharma Production Ab

Christer Nystrom

Anders Pettersson

Sten-Magnus Aquilonius

Susanne Bredenberg

Thomas Lundqvist

Thomas Hedner

Lennart Paalzow

There is provided a formulation suitable for transmucosal administration comprising a short acting hypnotic drug, which formulation provides a measurable plasma concentration of drug within 10 minutes of administration. The formulation is capable of providing sleep on demand, and preferably comprises particles of drug, for example zolpidem or a pharmaceutically-acceptable salt thereof and a mucoadhesion promoting agent, such as sodium carboxymethylcellulose, which particles of drug and mucoadhesive are presented upon the surface of larger carrier particles.

Pharmaceutical formulations useful in the treatment of insomnia

A pharmaceutical composition for the treatment of acute disorders is described. The composition comprises an essentially water-free, ordered mixture of at least one pharmaceutically active agent in the form of microparticles which are adhered to the surfaces of carrier particles which are substantially larger than the particles of the active agent or agents, and are essentially water-soluble, in combination with the bioadhesion and/or mucoadhesion promoting agent. The invention also relates to a method for preparing the composition and to the use of the composition for the treatment of acute disorders.

Pharmaceutical composition for the treatment of acute disorders

A pharmaceutical composition for the treatment of acute pain by sublingual administration is described. The composition comprises an essentially water-free, ordered mixture of fentanyl or a pharmaceutically acceptable salt thereof in the form of microparticles which are adhered to the surface of carrier particles which are substantially larger than the particles of fentanyl, and are essentially water-soluble. In a preferred embodiment, the composition also contains a bioadhesion and/or mucoadhesion promoting agent. The invention also relates to the preparation of the composition, and to the use of the composition for the treatment of acute pain.

Fentanyl composition for the treatment of acute pain

A medicine is supplied in the form of a number of small units, partial doses, containing a determined, equal quantity of the active medical substance, and a number of these units, which correspond to a predetermined dose quantity, total dose, of the active medical substance are taken out and dispensed to the consumer. A device for the carrying out of the procedure comprises devices for counting and feeding-out of a number of units, partial doses of the medicine, which correspond to a predetermined dose quantity of the active medical substance and for transport of these units to a dispensing device for dispensing of the above-mentioned dose quantity, total dose, to a consumer.

Method and apparatus for dosing a medical preparation

Diagnostic preparation for detection of helicobacter pylori

Pharmaceutical formulation

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Lidingo, Sweden

Christer Nystrom