Maze Therapeutics, Inc.

Chris Ziebenhaus

David John Morgans, Jr

Birong Zhang

Alexander Wayne Schammel

Patrick Sang Tae Lee

Christopher Joseph Sinz

Maarten Hoek

Todd Jonathan August Ewing

Victoria Anne Assimon

Adam Neil Reid

Sarah M Bronner

Provided herein are compounds of formula (II):

APOL1 inhibitors and methods of use

Provided herein are compounds of formula (II): or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein m, n, p, R, R, R, L, L, L, R, X, X, X, and Xare as defined herein. Also provided are methods of preparing compounds of formula (II), or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing. Also provided are methods of inhibiting APOL1 and methods of treating an APOL1-mediated disease, disorder, or condition in an individual.

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San Francisco, CA, United States of America

Chris Ziebenhaus