Catholic University Industry Academic Cooperation Foundation

The Catholic University of Korea Industry-academic Cooperation Foundation

The General Hospital Corporation

Postech Academy-industry Foundation

Korea Research Institute of Chemical Technology

The Industry & Academic Cooperation in Chungnam National University (iac)

Bmi Korea Co., Ltd

Phi Biomed Co., Ltd.

Biopolymed Inc.

Lucid Korea Co., Ltd.

The Industry & Academic Cooperation in Chungnam National University

Choun-Ki Joo

Jun-Sub Choi

Dong Jin Chang

Sung-Eun Yoo

Sei Kwang Hahn

Hyemin Kim

Young-Hoon Kim

Jin-Woo Kim

Sung-Hee Lee

Seok-Hyun Yun

Keon Jae Lee

Yoon Keun Kim

Jin-Ha Park

Hyun Soo Lee

Geun-Hyeog Lee

Myung-Ok Park

Eun Ju Oh

Jee-Hee Suh

Kyu-Yang Yi

Eunhee Kim

Koo Woo

Nam Sook Kang

Jeong-A Yang

Seung Kew Yoon

You Me Tae

Kitae Park

Ki Su Kim

Dohee Keum

Dong Kun Lee

Yeong-Jun Baik

Tae-Sung Koo

Hye-Sung Lee

Yun-Seok Cho

Wonhee Hur

Ehsan Kamrani

Chong Houn Lee

Sung-Sik Bang

Kyung-A Kim

Nack-Jeong Kim

Min-Young Park

Hyun-Ju Bae

Tae-Kyu In

Jae-Sik Yang

One aspect of the present disclosure relates to a remotely controllable lens device. The lens device can include a lens material and a circuit physically coupled to the lens material. The circuit can be configured to be powered based on an energy signal from a power source to perform a function (e.g., release of drug, generation of electromagnetic radiation, detection of electromagnetic radiation, and/or control of an optical refractive property). For example, the power source can be an external power source and/or an auto-powered source. The external power source can be, for example, a power source that utilizes synchronized magnetic flux phase coupling (e.g., WiTricity). The auto-powered source can be provided on-site (e.g., on-chip) using a harvesting system (e.g., solar-cell, photo-cell, piezoelectric, etc.)

Remotely controllable lens device

The present invention relates to a novel indene derivative, a preparation method for the same, and a pharmaceutical composition for treating retinal disease comprising the same as an active ingredient. The novel indene derivative of the present invention, the optional isomer of the same, or the pharmaceutically acceptable salts of the same have excellent inhibitory efficiency of receptor-interacting serine-threonine-protein kinase 1 (RIPK1). Therefore, the composition containing the same as an active ingredient can be effectively used as a pharmaceutical composition for treating retinal disease.

Fused heterocyclic ring compounds and method of treating retinal disease using same

The present invention provides a pharmaceutical composition for preventing or treating macular degeneration, which comprises benzopyran derivatives substituted with secondary amines including imidazole or pharmaceutically acceptable salts thereof as an active ingredient. The pharmaceutical composition of the present invention may be used in the form of eye drops.

Pharmaceutical composition for preventing or treating macular degeneration

The present invention relates to a composition for treating an ocular inflammatory disease, comprising hydrophilic sulfasalazine and hyaluronic acid, and a preparation method therefor. Furthermore, the present invention relates to a method for treating an ocular inflammatory disease, which comprises administering, to an individual, a therapeutically effective amount of hydrophilic sulfasalazine and hyaluronic acid.

Eye drop composition for treating ocular inflammatory disease and preparation method therefor

The present invention relates to an anterior capsulotomy guide device for cataract surgery. The present invention relates to an anterior capsulotomy guide device for cataract surgery which is temporarily inserted for anterior capsulotomy during cataract surgery, wherein the anterior capsulotomy guide device comprises a ring-shaped body, and a cut portion is formed by cutting a part of the body. According to the present invention, it is possible to carry out anterior capsulotomy with precise size and shape during cataract surgery, thereby maximizing the effect of cataract surgery.

Anterior capsulotomy guide device for cataract surgery

The present invention relates to a method of inducing differentiation of a stem cell into a corneal limbal stem cell, and a medium composition used therein. Further, the present invention relates to a pharmaceutical composition for treating corneal damage, including a corneal limbal stem cell differentiated using the above-described method as an active ingredient.

Method of inducing differentiation of stem cell into corneal limbal stem cell

The present invention provides a system and a method for performing a cataract surgery. The system of the present invention includes an optical coherence tomography apparatus, an image capturing device, and a central processing unit. The method includes imaging optical coherence tomography of a patient's eye using the optical coherence tomography apparatus, capturing the patient's optical coherence tomography with the image capturing device, generating a 3D image and coordinates of the patient's eye, and determining a central location of a pupillary margin and an iridocorneal angle using a central processing unit. The center of the anterior capsule of the human crystalline lens is then calculated by matching the iridocorneal angle to the central location of the pupillary margin.

System for calculating center of anterior capsule and method thereof

The present invention relates to an ocular surgery training device, which includes an eye model having a hole at one side, and a catheter inserted into the hole, wherein a pressure sensor for measuring a pressure applied to the hole by the catheter is provided at one end of the catheter. The present invention may provide the ocular surgery training device which may enhance the skill of users in performing ocular surgery, thereby preventing complications.

Device for ocular surgery training

The present invention relates to a surgical instrument for cataract surgery, and provides the surgical instrument for assisting in distinguishing the anterior capsule during cataract surgery, including a ring-shaped body; and a light source provided on a bottom surface portion of the body.

Surgical instrument for assisting in distinguishing anterior capsule during cataract surgery

The present invention relates to a composition for inhibiting after-cataract including a hydrophilic sulfasalazine; a high content of hyaluronic acid; and a carrier containing an aqueous solution, and a method of preparing a composition for inhibiting after-cataract including the steps of adding hyaluronic acid powder to a hydrophilized sulfasalazine; and mixing the same with a specific condition.

Composition for inhibiting after-cataract and method of preparing the same

The present invention relates to a drug delivery composition comprising a hyaluronic acid-peptide conjugate micelle and a production method thereof. According to the drug delivery composition and the production method of the drug-loaded, hyaluronic acid-peptide conjugate micelle of the present invention, the reaction for encapsulating can proceed in a mixed solvent of an aqueous solvent and an organic solvent. Therefore, the present invention can be applied to various types of water-insoluble active components and the biocompatible and biodegradable derivative can encapsulate a drug to provide a drug-loaded micelle, which is safe to be applied for human bodies. Moreover, the micelle has a therapeutic effect from the peptide contained therein, which can act in combination with the drug as packing therein. Therefore, the drug delivery composition and its production method can be utilized in the field of producing a sustained release formulation with an extended duration of the medicinal effect.

Drug delivery system using hyaluronic acid-peptide conjugate micelle

The present invention relates to a siRNA which targets mRNA of the NF-Kappa B p105 gene to cause its degradation by RNAi induction. In addition, the present invention provides a pharmaceutical composition for the treatment of diseases associated with aberrant cell proliferation and migration, comprising the siRNA and delivery vehicle capable of intracellular delivery of the same.

siRNA of NF-kB p105 for inhibiting cell proliferation and migration and a composition comprising same

Growing community of inventors

Seoul, South Korea

Choun-Ki Joo