Elanco Tiergesundheit Ag

Novartis Tiergesundheit Ag

Chouaib Tahtaoui

Pierre Ducray

Pascal Furet

Francois Pautrat

Steve Nanchen

Chikako Ogawa

Denise Rageot

Jean-Luc Perret

Peter Rolfe

Emilie Dupont

Sarah George

The present invention provides compounds of formula (I):

Bicyclic derivatives for treating endoparasites

The present invention provides a method of treating liver fluke infections in a mammal in need of such treatment comprising administering an effective amount of diamphenethide in combination with an effective amount of clorsulon.

Potentiation of helminth treatment

The present invention provides a dihydroisoxazole of formula: or a salt thereof, for use in the control of sea lice in fish. 

Dihydroisoxazole compound for use in controlling sea lice

The present invention relates to a new compound of formula (I) wherein the variables have the meaning as indicated in the claims; or an enantiomer or salt thereof. The compounds of formula (I) are useful in the control of parasites, in particular endoparasites, in and on vertebrates. 

Sulfonylaminobenzamide compounds as anthelmintics

The invention relates to a compound of formula (I) wherein the variables have the meaning as indicated in the claims; in free form and in salt form; and optionally the enantiomers and geometrical isomers thereof. The compounds of formula (I) are useful as therapeutic agent for organ transplants, lupus, multiple sclerosis, rheumatoid arthritis, psoriasis. Type I diabetes and complications from diabetes, cancer, asthma, atopic dermatitis, autoimmune thyroid disorders, ulcerative colitis, inflammatory bowel diseases, Crohn's disease, Alzheimer's disease, leukemia, osteoarthritis, control of pruritus, chronic respiratory disease or keratoconjunctivitis in mammals. 

Heterocyclyl-substituted cyclohexylsulfonamides as JAK inhibitors

The invention relates to a compound of formula (I) wherein the variables have the meaning as indicated in the claims; in free form and in salt form; and optionally the enantiomers and geometrical isomers thereof. The compounds of formula (I) are useful as therapeutic agent for organ transplants, lupus, multiple sclerosis, rheumatoid arthritis, psoriasis, Type I diabetes and complications from diabetes, cancer, asthma, atopic dermatitis, autoimmune thyroid disorders, ulcerative colitis, inflammatory bowel diseases, Crohn's disease, Alzheimer's disease, leukemia, osteoarthritis, control of pruritus, chronic respiratory disease or keratoconjunctivitis in mammals. 

Compounds

Sulfonylaminobenzamide compounds

The present invention relates to new compounds of formula (I) wherein the variables have the meaning as indicated in the claims; in free form and in salt form; and optionally the enantiomers and geometrical isomers thereof. The compounds of formula (I) are useful in the control of parasites, in particular ectoparasites, in and on vertebrates. 

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Rixheim, France

Chouaib Tahtaoui