Centocor, Inc.

Janssen Biotech, Inc.

Centocor Ortho Biotech Inc.

Chong C Huang

Michael Naso

Bailin Liang

Robert T Sarisky

Lani Rose San Mateo

Karen Duffy

Xiao-Yu R Song

Roberta Lamb

Katherine Li

Li Li

Xiaozhou Shang

Mouhamadou L Mbow

Keying Ma

Farhat Syed

Guihua Liu

Karen E Duffy

Mateo Lani San

Compositions and methods are provided for measuring and determining biomarkers for IL-13.

Compositions and methods for IL-13 biomarkers

Toll Like Receptor 3 (TLR3) modulators, such as antibodies, polynucleotides encoding TLR3 antibodies or fragments thereof, and methods of making and using the foregoing are disclosed.

Antibody reactive with human toll like receptor 3

Novel polypeptides (CNGH0010) and antibodies, including specified portions or variants, specific for at least one such CNGH0010 polypeptide, variant, or fragment thereof, as well as nucleic acids encoding such CNGH0010 polypeptides and antibodies, complementary nucleic acids, vectors, host cells, and methods of making and using thereof, are useful for therapeutic and diagnostic formulations, administration and devices. The aforesaid polypeptides can be used to generate human, primate, rodent, mammalian, chimeric, humanized and/or CDR-grafted anti-CNGH0010 antibodies. The CNGH0010 polypeptides and antibodies are used in modulating or treating at least one CNGH0010-related disease in a cell, tissue, organ, animal, or patient. Such diseases may include, but are not limited to, psoriasis, rheumatoid arthritis, emphysema, asthma, diabetes, autoimmune thyroiditis, inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, different types of dermatitis including allergic dermatitis, contact dermatitis, actinic keratosis, wound healing, scar formation, various renal diseases, various respiratory diseases, various diseases of reproductive organs, such as endometriosis, melanoma, squamous cell carcinoma, ovarian cancer, breast cancer, lung cancer, colon cancer, prostate cancer, renal cell carcinoma, Grave's diseases and other inflammatory and hyperproliferative diseases.

CNGH0010 specific polynucleotides, polypeptides, antibodies, compositions, methods and uses

Growing community of inventors

Paoli, PA, United States of America

Chong C Huang