Animal Technology Institute Taiwan

Chon Ho Yen

Chuan Mu Chen

Shau Ping Lin

Shinn Chih Wu

Mei Ling Lin

Teng Kuei Cheng

Ping Cheng Yang

The present invention refers to a method of separating casein from animal milk, especially, after defatting the animal milk as the pretreatment, the processing of the defatted milk aforesaid through a ceramic filtration membrane to remove the casein in the milk. The pretreatment process of separating the casein from the milk is then complemented by other processes of purification, so as to obtain the target protein of higher purity.

Method of separating protein from animal milk

The present invention discloses a method for expressing multiple recombinant proteins in transgenic non-human mammalian milk, characterized in which human clotting factor IX gene and porcine lactoferrin gene are transferred into the mammal by gene injection and embryonic implantation to obtain expression in the milk of transgenic mammal and its filial generation. The method of this invention can maintain the stable expression of multiple recombinant proteins in the transgenic mammal during lactation and stable expression amount proximate to that of the first generation in the offsprings of the transgenic non-human mammal.

Method for expressing multiple recombinant proteins in milk of transgenic non-human mammals

Growing community of inventors

Miaoli, Taiwan

Chon Ho Yen