Korea Research Institute of Bioscience and Biotechnology

Korea Research Institute of Chemical Technology

Cho Rok Jung

Mi Young Son

Kyung Sook Chung

Janghwan Kim

Kwang Bo Jung

Sun Woong Kang

Hana Lee

Myung Jin Son

Jung Hwa Lim

Hyun Mi Kang

Kyung Hee Noh

Kyeong-Ryoon Lee

Ohman Kwon

Soo Jin Oh

Hyun Soo Cho

Sang Soo Han

The present invention relates to a method for preparing a human intestinal epithelial model. The human intestinal epithelial model, prepared by the method according to the present invention, has all characteristics of goblet cells, enteroendocrine cells, and Paneth cells, and thus can highly mimic the function of actual human intestinal cells, so that the human intestinal epithelial model can be effectively used for development of new drugs, evaluation of drug absorption and toxicity, or evaluation of engraftment of intestinal microorganisms, or as a composition for in vivo transplantation.

Human intestinal epithelium model and method for preparing same

Provided are a method of preparing in vitro-matured intestinal organoids, and intestinal organoids prepared by the method.

Method of preparing in vitro-matured human intestinal organoids and use thereof

A cell culture vessel according to the present invention is characterized by comprising a first vessel having a stirring member disposed therein, and a second vessel configured to be inserted in the interior of the first vessel and having a hole for allowing a solvent accommodated in the first vessel to pass through the interior thereof, wherein the stirring member is arranged in a recess portion formed in the first vessel.

Cell culture receptacle

The present disclosure provides a biomimetic cell culture apparatus that mimics interactions among organs in a human body. The present disclosure includes a plurality of culture units for culturing cells, a conduit for connecting the plurality of culture units to each other to form a circulating path, a pump unit disposed on the conduit for forming a flow in culture medium such that the culture medium circulates through the plurality of culture units, and an agitating module for agitating the plurality of culture units.

Biomimetic cell culture apparatus and cell culture system comprising the same

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Daejeon, South Korea

Cho Rok Jung