Roche Molecular Systems, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Chitra Manohar

Xiaoju Max Ma

Huan Truong

Cindy Cheung

Grantland Hillman

Eugene G Spier

Ann Begovich

Alison Tsan

Jingtao Sun

Kalyani Mangipudi

Lily Wong

Christopher David Santini

Marintha Heil

Marcel Fontecha

Ellen C Ordinario

Dwight Kuo

Jaya Rajamani

Michelle Elizabeth Yee

Thanh Tam

Ramani Sadanandam Ravirala

Javelin Chi

Michael Lee

Ellen Ordinario

Methods for the rapid detection of the presence or absence of SARS-CoV-2, influenza A and influenza B in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers and probes targeting SARS-CoV-2, influenza A, and influenza B and kits are provided that are designed for the detection of SARS-CoV-2, influenza A and influenza B.

Compositions and methods for detecting Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Influenza A and Influenza B

Provided herein are methods and compositions to detect MET exon 14 skipping using RT-PCR, and methods of treating individuals with MET exon 14 deleted cancers.

Detection of MET exon 14 deletions and associated therapies

Provided herein are methods and compositions for multiplex detection of a large number of actionable gene fusions with very high sensitivity and specificity. The present methods and compositions can detect ALK, RET, and ROS1 gene fusions, optionally in combination with other mutations and fusions.

Multiplex PCR detection of ALK, RET, and ROS fusions

The invention comprises reagents and methods for detecting cancer-associated mutations in the human EZH2 gene. Further, a method of detecting the mutations and a method of treatment are disclosed.

Methods and compositions for detecting mutation in the human EZH2 gene

Growing community of inventors

San Ramon, CA, United States of America

Chitra Manohar