Novaflux Inc.

Princeton Trade & Technology, Inc.

Other

Olympus Corporation

United States of America As Represented by the Secretary of the Air Force

Princeton Trade and Technologt, Inc

Ching-Yue Lai

Mohamed Emam Labib

Stanislav S Dukhin

Yacoob Tabani

Peter A Materna

Jeffrey Charles Robertson

James L Manganaro

Joseph J Murawski

Geoffrey Lawrence Mahon

Seo Yean Sohn

Ziye Qian

Charles B Carroll

Provided among other things are a cleaning composition comprising a carrier fluid comprising in the carrier fluid polymer comprising particulate super absorbent polymer (PSAP), wherein the PSAP as in the cleaning composition is substantially at the percolation volume fraction or higher; wherein the cleaning composition can be passed over a surface driven by a pressure drop effective to render the composition traditional biofilm (TBF) cleaning effective and protein cleaning effective.

Cleaning composition with superabsorbent polymer

Provided among other things is a cleaning composition comprising: a carrier fluid; and Minute Fibrils suspended in the carrier fluid, wherein the composition is protein cleaning effective.

Compositions for cleaning and decontamination

Provided among other things is a sampling system for determining an amount or type of contamination a narrow, elongated passageway in a medical device, said sampling system comprising: (a) a fluid supply system that supplies to said passageway a sampling liquid for flowing through said passageway and a gas for flowing through said passageway; and (b) a receiving container that receives liquid from said passageway, wherein said sampling liquid is sterile, wherein said sampling liquid is configured to allow recovery of viable pathogens from the passageway, and wherein said sampling liquid comprises an amount and selection of surfactant effective to enhance the dislodgement ofandbacteria from the narrow passageways.

Apparatus and methods for hygiene testing a medical device

Hollow fiber drug delivery devices are described. Device can contain structural or solid fibers. Fabric can be formed by fibers being interwoven or joined to each other. All or some of the fibers can be resorbable. Fibers can be subdivided, by deformations or closure points, into numerous compartments that separately deliver drug. Deformations can be located at points of fiber intersection or joining. Different drug or drug formulation can be provided in different places. Fibers can be given appropriate surface treatments or coatings to achieve desired properties such as wetting of pores and surfaces. Different release characteristics in different directions can be achieved. The hollow fibers can contain solid particles of drug, and can contain gel. Possible applications include hernia meshes, pouches, sutures, catheters, wound dressings, stents, nerve regrowth guides, refillable/drainable devices, and devices that deliver drug to lymphatic flow.

Implants and constructs including hollow fibers

A method for cleaning an internal surface of a narrow diameter channel includes steps of: flowing a liquid cleaning medium and a gas through the narrow diameter channel under a flow regime that creates surface flow entities in contact with and sliding along the internal surface of the narrow diameter channel, the surface flow entities having three-phase contact lines and associated menisci, the surface flow entities detaching contaminants with which they come in contact from the internal surface of the narrow diameter internal surface of the narrow diameter channel; and rinsing the internal surface of the narrow diameter channel to remove residual liquid cleaning medium and detached contaminants from the channel.

Method for composition for cleaning tubular systems employing moving three-phase lines

Apparatus and methods are disclosed for cleaning interiors of passageways in endoscopes or other luminal medical devices by flow of liquid and gas therethrough. The liquid flow may include rivulets, droplets or other liquid entities which move on the internal surfaces of the passageways, and may include a three-phase contact interface between liquid and dry solid and gas.

Method for cleaning passageways using flow of liquid and gas

Method for cleaning passageways such an endoscope channels using flow of liquid and gas

The narrow diameter channel has a diameter of about 0.02 centimeter to about 1.6 centimeters and a length of about 0.75 meter to about 5 meters. The internal surface of the narrow diameter channel is hydrophobic, and the surface flow entities exhibit an advancing contact angle of greater than 50 degrees and a receding contact angle of greater than zero degree. The detachment of contaminants from the internal surface of the narrow diameter channel is produced by a sweeping of the internal surface of the narrow diameter channel with the three-phase contact lines of the surface flow entities, the cleaning medium is not predispersed in the gas before entering the channel, and less that 10% of the surface of the channel is covered by a contiguous annular film.

Method and composition for cleaning tubular systems employing moving three-phase contact lines

A method of cleaning surfaces using a mixed phase cleaning mixture of an aqueous solution and a flow of gas sufficient to produce droplets of the liquid which are entrained by the gas for a time sufficient to clean tubing of various lengths and geometries and porous membranes to remove biofilm, debris and contaminants.

Method of cleaning passageways using a mixed phase flow of a gas and a liquid

Biofilm and debris can be removed from the interior and exterior surfaces of small bore tubing by passing an aqueous cleaning solution of water, one or more surfactants and preferably a source of hydrogen peroxide, optionally including small inert solid particles, together with a gas under pressure, to create a turbulent flow within the tubing that loosens the biofilm and debris so that they can be flushed from the tubing. When the exterior surfaces of tubing are to be cleaned, the tubing is inserted in a sleeve fitted with an adaptor that provides a pressure-tight seal between the tubing and the sleeve.

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Pennington, NJ, United States of America

Ching-Yue Lai