National Taiwan University

Gnt Biotech & Medicals Corporation

Ching-Yi Lin

Chia-Nan Chen

Wei-Jan Huang

Li-Ling Chi

Kuang-Wen Liao

Ye-Su Chao

Yi-Hong Wu

Rea-Min Chu

Ya-Wen Hsiao

Meng-Ju Tsai

Yu-Jung Liao

Wan-Yi Hsu

Huan-Yu Lin

The invention provides a pH-sensitive linker that can simultaneously bind metallic nanoparticles and one or more agents with various molecular size. The linker of the invention can deliver the agents into cells involved in disease processes or close to cells so that the agents can selectively target and effect on the cells. The target delivery provided by the linker of the invention can be used for example for disease sensing, imaging, drug delivery, and therapy.

PH-sensitive linkers for delivering a therapeutic agent

Disclosed is a complex immuno-gene medical composition for activating NK cells to enhance a host immune system. The composition includes a plurality of cytokines, including Th1 and Th2 cytokines. Th2 cytokines antagonize TGF-&#x3b2; inhibiting NK cells to disable the inhibition of the immune system. Th1 cytokines activate NK cells in a host to enhance the host's ability to fight against tumor cells. By use of the complex immuno-gene medical composition, removal of tumor cells is expected.

Complex immuno-gene medical composition for inhibiting tumor cells

Growing community of inventors

Taipei, Taiwan

Ching-Yi Lin