Aventis Pharmaceuticals Inc.

William H. Rorer, Inc.

Rhone-poulenc Rorer Pharmaceuticals Inc.

Aventis Pharmaceuticals Products Inc.

Ching T Tsuei

Patrick Leon

Michael K O'Brien

Tory H Powner

Laurence W Reilly

Julius Diamond

Matthew R Powers

Luc Grondard

Benoit J Vanasse

Adam W Sledeski

Gregory G Kubiak

Herve Garcia

Thomas Goetzen

Walter Rodriquez

Laurence Pailleres-Hubert

Benoit Viguier

Francis L Walther

Michael D Thompson

Harshavadan C Shah

This invention is directed to a process for preparing N6-substituted adenosine derivatives, to intermediates useful therefor and to methods of preparing these intermediates.

Process for preparing N6-substituted adenosine derivatives

This invention is directed to methods for the preparation of [1S-[1a,2b,3b,4a(S*)]]-4-[7-[[1-(3-chloro-2-thienyl) methyl]propyl]amino]-3H-imidazo[4,5-b]pyridin-3-yl]-N-ethyl-2,3-dihydroxyc yclopentanecarboxamide, methods for the preparation of intermediates thereto, and to said intermediates themselves.

Preparation of

Disclosed is a process for the preparation of 2-aryl-1-cyclohexene-1-carboxaldehydes from 1-arylcyclohexenes which are intermediates for trans-6-[(2-arylsubstituted cycloalkenyl and substituted cycloalkyl)alkenyl and alkyl]-3,4,5,6-tetrahydro-2H-pyran-2-ones.

Synthesis of aldehydes useful in the preparations of HMG-CoA reductase

Novel naphthylalkanoic acids and their derivatives are described. Therapeutic compositions and method of treatment of inflammation is also disclosed.

Alpha-acyl substituted naphthylacetic acids

Growing community of inventors

Lansdale, PA, United States of America

Ching T Tsuei