The United States of America As Represented by the Secretary of

United States of America, As Represented by the Secretary of Agriculture

Ching T Hou

Tsung Min Kuo

The compound 7,10,12-trihydroxy-8(E)-octadecenoic acid (TOD) has been produced by bioconversion of ricinoleic acid by,PR3. TOD and derivatives thereof are useful for controlling biological organisms, such as fungi and insects.

7,10,12-trihydroxy-8(E)-octadecenoic acid and derivatives and uses thereof

A strain of Pseudomonas Sp. bacterium (NRRL B-18602) has been discovered which is capable of converting oleic acid to the novel compound, 7,10-dihydroxy-8-octadecenoic acid (DOD). The production of DOD is unique in that it involves a hydroxylation at two positions and a rearrangement of the double bond of the substrate molecule. The new multifunctional, long-chain aliphatic acid has potential utility as a plasticizer and as a source of intermediates in the synthesis of specialty chemicals.

Microbial production of a novel compound 7,10-dihydroxy-8-octadecenoic

A novel compound, 12,13,17-trihydroxy-9(Z)-octadecenoic acid (THOA) was produced from linoleic acid by microbial transformation at 25% yield. The newly isolated microbial strain catalyzing this transformation was identified as Clavibacter sp. ALA2 (Accession No. NRRL B-21660). THOA and its derivatives have application as antifungal agents.

Growing community of inventors

Peoria, IL, United States of America

Ching T Hou