Institute of Nuclear Energy Research

Institute of Nuclear Energy Research, Taiwan, R.o.c.

Ching-Hohn Len

Zei-Tsan Tsai

Chia-Chieh Chen

Ko-Shao Chen

Bin Lin

Te-Hsing Wu

Chi-Man Ho

Shu-Yi Deng

A novel method of preparation of easily stripped off temporary wound dressing material is disclosed. In this process, the-N-isopropyl acrylamide (NIPAAm) monomer is successfully grafted on the non-woven cloths by copolymerization. It is initiated by .gamma.-ray irradiation to activate the surface of the non-woven cloth. NIPAAm is then grafted onto the surface of the non-woven cloth. The free radical or peroxide is produced by Co-60 .gamma.-ray, then grafted on the non-woven cloths. The lower critical solution temperature (LCST) in thermoresponsive poly-N-isopropylacrylamide (NIPAAm) is still retained after the grafting. This will make the dressing cloth stripped off easily and without hurting the tissue. The material process is very simple and has medically applicable value.

Preparation of easily stripped off temporary wound dressing materials by

The invention relates to a method for synthesis of poly(L-leucine). Without any initiator and solvent poly(L-leucine) has been made from L-leucine-N-carboxy anhydride as starting material in the solid state by irradiation with gamma ray. There is only one step in the entire synthetic processing, and the polymerization yield is 100% and the process is a very simple, safe and convenient method. The poly(L-leucine) is one of the best materials for temporary wound dressing.

Synthesis of poly(l-leucine)

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Taipei, Taiwan

Ching-Hohn Len