Industrial Technology Research Institute

Ching-Fang Lu

Cheng-Tai Chen

Tzu-Ling Tseng

Wei-Ya Lin

Mary Ya-Ping Yeh

Yi-Ting Chen

Tsai-Wei Hsu

Chwei-Shiun Yang

Pei-Shin Jiang

Ting-Hsuan Chen

Chia-Chen Chang

Kuo-Hsing Wen

Yi-Chen Liu

Shih-Ya Chen

Erh-Fang Lee

Ya-Hui Chiu

Nien-Tzu Chou

Ting-Shuo Chen

A cell activation reactor and a cell activation method are provided. The cell activation reactor includes a body, a rotating part, an upper cover, a microporous film, and multiple baffles. The body has an accommodating space, which is suitable for accommodating multiple cells and multiple magnetic beads. The rotating part is disposed in the accommodating space and includes multiple impellers. The microporous film is disposed in the accommodating space and covers multiple holes of the accommodating space. The baffles are disposed in the body. When the rotating part is driven to rotate, the interaction between the baffles and the impellers separates the cells and the magnetic beads.

Cell activation reactor and cell activation method

A method of detecting a biological sample includes the following steps. A magnetic sensor chip is provided, wherein the magnetic sensor chip includes a substrate and a magnetic sensing layer located on the substrate. Probes are connected to the magnetic sensor chip. A sample solution containing biological samples labeled with a first marker is provided on the magnetic sensor chip, so that the biological samples labeled with the first marker are hybridized with the probes. Magnetic beads labeled with a second marker are provided on the magnetic sensor chip, so that the magnetic beads labeled with the second marker are bound onto the biological samples labeled with the first marker. A signal sensed by the magnetic sensing layer is detected by a magnetic sensor.

Method of detecting biological sample

Use of urine biomarkers for diagnosing nephropathy, monitoring nephropathy progress, and assessing efficacy of a nephropathy treatment. These urine biomarkers include leukocyte-associated Ig-like receptor-2, alpha-1 acid glycoprotein, their fragments, and combinations thereof.

Biomarkers associated with nephropathy

Growing community of inventors

Zhubei, Taiwan

Ching-Fang Lu