Toagosei Company, Ltd.

Japan Tissue Engineering Co., Ltd.

Chikara Shinohara

Tetsuhiko Yoshida

Nahoko Kobayashi

Mikio Niwa

Ken-ichiro Hata

Masatoki Watanabe

Ken-Ichiro Hata

A method for manufacturing at least one kind of eukaryotic cells or a biosynthetic substance derived from the eukaryotic cells by proliferating the cells, which includes preparing an artificially synthesized peptide for promoting proliferation of the at least one kind of eukaryotic cells, incubating the eukaryotic cells in a culture medium, and adding the synthesized peptide at least once to the culture medium during the incubation process. The synthesized peptide includes an amino acid sequence selected from SEQ ID NOS: 1 to 18, and an amino acid sequence selected from SEQ ID NOS: 19 to 97.

Cell proliferation-promoting peptide and use thereof

A cell proliferation promoter includes, as an active ingredient, an artificially synthesized peptide that includes (A) an amino acid sequence constituting a membrane-permeable peptide and (B) an amino acid sequence selected from SEQ ID NOs: 19 to 103 or an amino acid sequence formed by substituting, deleting and/or adding one or several amino acid residues in the selected amino acid sequence.

Growing community of inventors

Gamagori, Japan

Chikara Shinohara