Toyota Jidosha Kabushiki Kaisha

Chika Asada

Chikara Ohto

Tokuzo Nishino

Shinichi Ohnuma

Kazutake Hirooka

Hisashi Hemmi

Yoshie Takeuchi

Manabu Suzuki

Yuka Higuchi

The present invention discloses a mutated enzyme comprising a geranylgeranil diphosphate synthase having its origin in wild type Sulfolobus acidocaldarius wherein at least one of phenylalanine at position 77, methionine at position 85, valine at position 99, tyrosine at position 101, phenylalanine at position 118, arginine at position 199 and aspartic acid at position 312 is substituted with another amino acid.

Process for the production of prenyl diphosphate using mutants of

The present invention discloses a mutated enzyme comprising a geranylgeranil diphosphate synthase having its origin in wild type Sulfolobus acidocaldarius wherein, at least one of phenylalanine at position 77, methionine at position 85, valine at position 99, tyrosine at position 101, phenylalanine at position 118, arginine at position 199 and aspartic acid at position 312 is substituted with another amino acid.

Nucleic acid encoding mutant geranylgeranyl diphosphate synthase

Long-chain prenyl diphosphate synthase

DNA coding for thermostable geranylgeranyl diphosphate (GGDP) synthase derived from Sulfolobus acidocaldarius is provided. The DNA is useful for production of GGDP synthase, which is, in turn, useful for production of GGDP.

Geranylgeranyl diphosphate synthase and DNA coding therefor

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Toyota, Japan

Chika Asada