Stolle Milk Biologics, Inc.

Chiharu Kubo

Lee R Beck

Shinji Murosaki

Atsunori Ishida

Yoshio Hidaka

Yasunobu Yoshikai

Kikuo Nomoto

The invention relates to the use of hyperimmune milk derived from milk producing animals hyperimmunized with bacterial antigens including intestinal bacteria. The present hyperimmune milk effectively prevents the decline of immunological functions observed in aging or immunocompromised animals and prevents the translocation of indigenous enteric bacteria from the GI tract of immunocompromised or aged animals, thereby preventing indigenous infection. More specifically, the present hyperimmune milk is administered to an animal in an amount sufficient to effectively prevent translocation of indigenous enteric bacteria in, delay the onset of, lower the rate of, or restore the declining immune functions of, aging or otherwise immunocompromised animals.

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Hakata-ku, Japan

Chiharu Kubo