Industrial Technology Research Institute

Other

Chih-Wei Ho

Chao-Chi Pan

Jia-Huey Tsao

Bor-Iuan Jan

Cheng-Tao Wu

Wen-Hsun Kuo

Yao-Sung Chang

Zu-Sho Chow

Yu-Ching Liu

Chung-Fan Chiou

Hsi-Hsin Shih

Chien-Tsung Wu

Bor-Iaun Jan

Jian Je Jian

The invention discloses an on-spot hydrophilic enhanced slide/microarray. The preparation method relates to a hydrophobic copolymer prepared by blending, grafting or co-polymerization of a hydrophobic material and a compound bearing functional groups such as anhydride, imide, cyclic amide, and cyclic ester, and application of the hydrophobic copolymer onto an organic or inorganic substrate. The resulting slide has the properties of on-spot hydrophilic/hydrophobic dynamic conversion, as well as on-spot hydrophilic enhancement for the preparation of high-density and high-efficiency bio-chip/microarray.

On-spot hydrophilic enhanced slide and preparation thereof

An on-spot selectively activated hydrophobic slide/microarray. The preparation method relates to a hydrophobic copolymer prepared by blending, grafting or co-polymerization of a hydrophobic material and a compound bearing a functional group protected by a protecting group, wherein the functional group is imide or cyclic amide, and the protecting group is a photo acid group such as a tosyloxy group. The hydrophobic copolymer coated on a substrate is then subjected to selective photolithographical activation so that the slide will have functional active copolymer spots separated by inactive copolymers. The resulting slide is suitable for the preparation of high-density and high-efficiency bio-chip/microarray.

On-spot selectively activated hydrophobic slide and preparation thereof

A hand-held electrophoresis detection device and support thereof. The hand-held electrophoresis detection device includes a support and a cartridge. The cartridge attaches a sample, and is disposed in the support in a detachable manner.

Hand-held electrophoresis detection device and support thereof

The invention features a method for preparing a high-density functional slide by coating a sol-gel containing amine-group bearing silanes and a solution containing polyaldehyde groups onto an organic or inorganic substrate, respectively. The resulting slide is useful in the preparation of highly homogeneous functional-group slides and the high-density and high-efficiency bio-chip/microarray.

High-density functional slide and preparation method thereof

A method is provided for preparing an active slide, including introducing a monomer containing an aldehyde group, or a mixture of a monomer containing an aldehyde group and an acidic functional group provider into a plasma chamber; and depositing the aldehyde group and acidic functional group onto the surface of an organic or inorganic matrix using plasma deposition to form a slide comprising a layer of polymerized actively functional groups thereon. The aldehyde groups and negatively charged groups are deposited on the surface of the active slide, such that the bio-molecules bound thereto possess the properties of an inducible orientation and thus form a mono-layer.

Activated inorganic slide having aldehyde groups deposited by plasma deposition

Growing community of inventors

Miaoli, Taiwan

Chih-Wei Ho