Tsinghua University

Nichem Fine Technology Co., Ltd.

Chien-Tien Chen

Chi-Chung Chen

Jwo-Huei Jou

Yi-Ya Liao

Shiue-Shien Weng

Wei-Shan Chao

Hao-Wei Liu

Ya-Pei Chen

Wei-Sheng Su

A method for preparing a cyclopeptide and a cyclopeptide preparing by the method are disclosed. The method includes the following steps: (a) providing compounds represented by formulas (I-1) and (I-4); (b) performing a reaction between the compounds of formulas (I-1) and (I-4) to obtain a compound represented by formula (I-5); (c) performing a reaction between the compound of formula (I-5) and the compound represented by formula (I-6) to obtain a compound represented by formula (I-7); (d) performing a cyclization reaction of the compound of formula (I-7) with a catalyst of formula (II) and deprotection to obtain a compound represented by formula (III), wherein the compounds of formulas (I-1), (I-4) to (I-7), (III) and the catalyst of formula (II) are as defined in the specification.

Cyclopeptide and method for preparing the same

A method for preparing a cyclopeptide and a cyclopeptide preparing by the method are disclosed. The method includes the following steps: (A) providing compounds represented by the following formulas (I-1) and (I-2):  and (C) performing a cyclization reaction of the compound of formula (I-3) with a catalyst of formula (II) and deprotection to obtain a compound represented by the following formula (III): 

Cyclic RGD peptide and method for preparing the same

A method for oxidative cleavage of a compound with an unsaturated double bond is provided. The method includes the steps of:  

Method for oxidative cleavage of compounds with unsaturated double bond

A block copolymer and a method for preparing the same are disclosed. The method comprises the following steps: (A) mixing a compound of formula (I), a catalyst of formula (II), and a first solvent to obtain a first mixture; (B) adding a first monomer into the first mixture for reaction to obtain a second mixture; and (C) adding a second monomer into the second mixture for reaction to obtain a third mixture; wherein the compound of formula (I) and the catalyst of formula (II) are as defined in the specification.

Block copolymer and method for preparing the same

An esterification method of a copolymer is disclosed. The esterification method includes the steps of: (A) mixing a copolymer having a carboxylic acid group, an alcohol or an aminoalcohol compound, a catalyst of formula (I), and a first solvent to obtain a first mixture; (B) reacting the first mixture at a predetermined temperature to obtain a second mixture; and (C) adding the second mixture into a second solvent; wherein the catalyst of formula (I) is shown below:[M(O)]X&#x2003;&#x2003;(I)wherein M, X, a, b, in, and n are defined in the specification.

Esterification method of copolymer

A method for preparing a cyclopeptide, which includes the following steps: (A) providing compounds represented by the following formulas (II-1) or (II'-1) and (II-2); (B) performing a reaction between the compounds of formulas (II-1) or (II&#x2032;-1) and (II-2), to obtain a compound represented by the following formula (II-3) and (II&#x2032;-3), respectively; (C) performing a reaction between the compound of formula (II-3) or (II&#x2032;-3) and a compound represented by the following formula (II-4) or (II&#x2032;-4), respectively, is performed, to obtain a compound represented by the following formula (II-5), and (II&#x2032;-5), respectively; (D) performing a cyclization reaction of the compound of formula (II-5) or (II&#x2032;-5) with a catalyst of formula (III), to obtain a compound represented by the following formula (I) or (I&#x2032;), respectively. The formulas (I), (I&#x2032;), (II-1) to (II-5), (II&#x2032;-1) to (II&#x2032;-5) and (III) are shown in the specification.

Method for preparing cyclopeptide

A cyclopeptide is disclosed, which is represented by the following formula (I) or (I'): wherein Ris defined in the specification. In addition, a pharmaceutical or cosmetic composition comprising the same and a method for preparing the same are also disclosed.

Cyclopeptide, pharmaceutical or cosmetic composition comprising the same and method for preparing the same

A novel compound is disclosed, which comprises: a 7-membered ring segment, which is formed by a cis-stilbene segment and a bridge atom with four bonds; and a fluorene segment connecting to the bridge atom with a double bond. In addition, an organic electronic device is also disclosed, and an organic layer therein comprises the novel compound of the present invention.

Compound and organic electronic device using the same

An organic compound is disclosed. The organic compound includes a cis-stilbene segment, a bridge atom segment having a bridge atom with four bonds, and the bridge atom is connected to the cis-stilbene segment with two of the four bonds to form a 7-membered ring structure, and an imidazole segment connected to the cis-stilbene segment.

Organic compound and electronic device using same

An organic compound is disclosed. The organic compound includes a cis-stilbene segment, a bridge atom segment having a bridge atom with four bonds, and the bridge atom is connected to the cis-stilbene segment with two of the four bonds to form a 7-membered ring structure, and a quinoxaline segment connected to the cis-stilbene segment.

The present invention provides a series of spirally configured cis-stilbene/fluorene hybrid compounds and an optoelectronic device comprising the same. The compound comprises a seven-membered ring portion. The seven-membered ring portion is composed of a cis-stilbene fragment, and a tetrahedral coordination bridging atom fragment, wherein the cis-stilbene fragment has at least one substituent, the substituent is independently a substituted or unsubstituted triazine group, pyrimidine group or phenyl group. The compounds have glass transition temperatures ranged from 156&#xb0; C. to 202&#xb0; C., decomposition temperatures ranged from 419&#xb0; C. to 509&#xb0; C., reversible electron transport property, and balanced charges motilities. In addition, a variety of experimental data have proved that these spirally configured cis-stilbene/fluorene hybrid materials can indeed be used as a hole-blocking type electron-transporter for phosphorescent OLEDs.

Spirally configured cis-stilbene/fluorene hybrid compounds and organic light emitting device comprising the same

The present invention provides a series of diphenylimidazole-fused, spirally configured cis-stilbene/fluorene hybrid compounds and an optoelectronic device comprising the same. The diphenylimidazole-fused, spirally configured cis-stilbene/fluorene hybrid compound bearing cyanoaryl and cyanoheteroaryl substituents, and have glass transition temperatures ranged from 154&#xb0; C. to 194&#xb0; C., decomposition temperatures ranged from 426&#xb0; C. to 443&#xb0; C., reversible electron transport property, and balanced charges motilities. In addition, a variety of experimental data have proved that these diphenylimidazole-fused, spirally configured cis-stilbene/fluorene hybrid materials can indeed be used as a hole-blocking type electron-transporter for phosphorescent OLEDs.

Diphenylimidazole-fused, spirally configured cis-stilbene/fluorene hybrid compounds and organic light emitting device comprising the same

The present invention provides a series of spirally configured cis-stilbene/fluorene hybrid materials, which are spirally-configured cis-stilbene/fluorene derivatives having glass transition temperatures ranged from 105&#xb0; C. to 130&#xb0; C., decomposition temperatures ranged from 385&#xb0; C. to 415&#xb0; C., reversible electron transport property, and balanced charges motilities. Moreover, a variety of experimental data have proved that the yellow fluorescent, the green phosphorescent, the yellow phosphorescent, and the red phosphorescent OLEDs using this spirally configured cis-stilbene/fluorene derivatives as the electron transport layers having hole blocking functions can indeed show excellent EQE, current efficiency, power efficiency, maximum luminance, and device lifetime performances much better than the conventional or commercial yellow fluorescent, green phosphorescent, yellow phosphorescent, and red phosphorescent OLEDs.

Spirally configured cis-stilbene/fluorene hybrid materials for organic light-emitting diode

An OLED (organic light emitting diode) comprises a series of spirally configured cis-stilbene/fluorene hybrid materials. The spirally configured cis-stilbene/fluorene hybrid materials are spirally-configured cis-stilbene/fluorene derivatives having the functions to block holes and constructed by at least one cis-Stilbene based component and at least one fluorene based component.

Spirally configured cis-stilbene/fluorene hybrid materials as hole-blocking type electron-transporters for OLED

The present invention provides a series of spirally configured cis-stilbene/fluorene hybrid materials, which are spirally-configured cis-stilbene/fluorene derivatives having glass transition temperatures ranged from 110&#xb0; C. to 135&#xb0; C., decomposition temperatures ranged from 380&#xb0; C. to 425&#xb0; C., reversible electron transport property, and balanced charges motilities. In addition, a variety of experimental data have proved that this spirally configured cis-stilbene/fluorene hybrid materials can indeed be used as a hole-blocking type electron-transporter and/or a host material for phosphorescent OLEDs. Moreover, the experiment data also reveal that the OLEDs using the spirally configured cis-stilbene/fluorene hybrid materials can indeed be used as the hole-blocking type electron-transporter or as a host materials, which are able to show excellent external quantum efficiency (&#x3b7;), current efficiency (&#x3b7;), power efficiency (&#x3b7;), maximum luminance (L), and device lifetime performances much better than the conventional or commercial OLEDs.

Growing community of inventors

Hsinchu, Taiwan

Chien-Tien Chen