Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan

Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.o.c

National Yang Ming Chiao Tung University

Chien-Chung Hsia

Mao-Chi Weng

Wuu-Jyh Lin

Kun-Liang Lin

Hsin-Ell Wang

Hao-Wen Kao

Kwan-Hwa Chi

Der-Chi Tien

Chao-Cheng Chen

Mei-Hui Wang

Po-Jung Chen

Cheng-Liang Peng

Chung-Hsin Yeh

Chun-Tang Chen

Disclosed herein is a complex, a contrast agent and the method for treating a disease related to CXCR4 receptor. The complex is configured to bind the CXCR4 receptor, and is used as a medicament for diagnosis and treatment of cancers and other indications related to the CXCR4 receptor.

Complex, contrast agent and method for treating a disease related to CXCR4 receptor

The present invention is related to a radiolabeled active targeting pharmaceutical composition, including: a bioconjugate and a radionuclide, wherein the bioconjugate includes a biomolecule and a metal nanoparticle, wherein the biomolecule has an affinity for receptors on the surface of a cell membrane and is selected from the group consisting of a peptide and a protein. The present invention further provides a method for evaluating a thermal adjuvant therapy for tumors and a kit thereof. The above-mentioned pharmaceutical composition is applied to evaluate a tumor accumulation time, so as to establish the optimal policy for a radiofrequency- or laser-induced thermal adjuvant therapy for tumors.

Radiolabeled active targeting pharmaceutical composition and the use thereof

Disclosed herein are a novel polymer, a thermosensitive carrier prepared using the same and use thereof. The novel polymer is essentially composed of a PEO-PPO-PEO block copolymer and silane.

Polymer, thermosensitive carrier and use thereof

Growing community of inventors

Taoyuan County, Taiwan

Chien-Chung Hsia