Nitto-denko Corporation

Chieko Kitaura

Lei Yu

Jian Liu

Gang Zhao

Masayuki Satake

Lisbeth Illum

Shigenori Morita

Masakatsu Urairi

Junichi Fujisawa

Tetsurou Ikeda

Reiko Akari

Shigeki Kawabe

Akinobu Souma

Zheng Hou

Katsuyuki Okubo

Kenjiro Minomi

Xinghe Wang

Keisaku Okada

Yucheng Song

Elizabeth Pearson

Chris Castello

Natsuko Kagehisa

Masashi Kamiyama

Martyn C Davies

Toshihiko Okazaki

An adhesive of the invention is used for polarizing plate to provide a transparent protective film on at least one side of a polarizer and comprises a resin solution comprising a polyvinyl alcohol-based resin, a crosslinking agent and a colloidal metal compound with an average particle size of 1 nm to 100 nm, wherein 200 parts by weight or less of the colloidal metal compound is added to 100 parts by weight of the polyvinyl alcohol-based resin. The adhesive for polarizing plate can reduce the occurrence of knicks.

Adhesive for polarizing plate, polarizing plate, manufacturing method therefor, optical film and image display

Disclosed herein are transmembrane transporter compounds containing guanidinium groups to enhance transport across biomembranes. Therapeutic and other biologically active moieties may be attached to the compounds. The transmembrane transporter compounds may include peptide nucleic acid monomer units.

Peptide nucleic  acid based guanidinium compounds

Disclosed herein are transmembrane transporter compounds containing guanidinium groups to enhance transport of a polymer backbone across biomembranes. Therapeutic and other biologically active moieties may be attached to the compounds. The polymer backbone may include peptide nucleic acid monomer units.

Peptide nucleic acid based guanidinium compounds

Disclosed herein are transmembrane transporter compounds containing guanidinium groups. Also disclosed herein are methods for transporting a biologically active moiety across a biological membrane using the transmembrane transporter compounds. Particularly, this invention provides a method for the delivery of a biologically active moiety across the biological membranes of such membranes as endothelial tissues.

Guanidinium delivery carriers

Compositions and methods are disclosed for the treatment of diabetes and related diseases using peptides with incretin hormone activity. Preferably, the peptide with incretin hormone activity is GLP-1, exendin or an analog of GLP-1 or exendin. The peptides with incretin hormone activity are administered transepithelially using a transepithelial carrier peptide. The transepithelial peptide contains sufficient amino, guanidine or amidino groups to stimulate transepithelial delivery. In some embodiments, the transepithelial carrier and the peptide with incretin hormone activity are embedded in a pressure sensitive adhesive layer of a plaster or patch.

Transepithelial delivery of peptides with incretin hormone activities

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Osaka, Japan

Chieko Kitaura