Hitachi High-tech Corporation

Hitachi-high-technologies Corporation

Chie Yabutani

Akihisa Makino

Masahiko Iijima

Sakuichiro Adachi

Naoto Suzuki

Rei Konishi

Shigeki Matsubara

Minoru Sano

Yuto Kazama

Takumi Yamada

Toshiyuki Inabe

Kenji Kogure

Takanori Sawada

Masato Ishizawa

Tatsuya Sakai

Kyoko Yamamoto

Satoshi Mitsuyama

Chihiro Manri

Toshiyuki Shimamori

Shinji Tarumi

Nobuhiko Sasaki

Hiroki Akase

Sumiko Murata

An automated analyzer includes two or more types of photometers to obtain suitable output of the measurement results of the plurality of photometers and suitable data alarm output even if there is an abnormality, or the like, at the time of measurement. The automated analyzer includes, for example, two types of photometers having different quantitative ranges and an analysis control unit for controlling analysis that includes measurement of a given sample using the two types of photometers. If two types of data alarms corresponding to abnormalities, or the like, during measurement have been added to the two types of measurement results from the two types of photometers, the analysis control unit selects measurement result and data alarm output corresponding to the combination of the two types of data alarms and outputs the same to a user as analysis results.

Automated analyzer and automated analysis method

The automatic analysis deviceis provided with: a specimen dispensing mechanismthat dispenses subject blood plasma and/or normal blood plasma to be added to correct the coagulation time of the subject blood plasma, into a plurality of specimen containers; reaction containersthat contain the subject blood plasma and/or the normal blood plasma; a reagent dispensing mechanismthat dispenses a reagent into the reaction containers; and a detecting unitwhich applies light from a light sourceto the subject blood plasma and/or the normal blood plasma to which the reagent is added in the reaction containers, and which measures the coagulation time on the basis of the obtained scattered light and/or transmitted light.

Automatic analysis device and automatic analysis method

It is necessary to efficiently agitate a small amount of sample (such as blood) and reagent (such as diluted solution) in a short time with a dispensing probe having a constant tube inner diameter. An automatic analysis device, by a dispensing probe, executes an aspiration step of aspirating a reagent from a reagent vessel; a first dispensing and aspiration step of dispensing a first liquid amount of the aspirated reagent to a reaction vessel and aspirating, from the reaction vessel, a second liquid amount of a mixed liquid obtained by mixing the reagent and the sample in the reaction vessel; and a final dispensing step of dispensing the aspirated mixed liquid and the reagent in a predetermined dispensing amount. A first liquid amount Va is less than a predetermined dispensing amount Vdil.

Automatic analysis device

A chemical dispensing mechanism detects the liquid surface of a chemical including a chemical container mounted on a chemical disk. A calculation control unit controls the operation of the chemical dispensing mechanism. The calculation control unit performs a first raising operation, in which a chemical stored in the chemical container is suctioned by the chemical dispensing mechanism, which is then raised up to a first bubble detection position, determines whether a liquid surface is present, and outputs an alert indicating the presence of a bubble on the liquid surface when the liquid surface has been determined to be absent. The first bubble detection position is when the tip of a dispensing nozzle of the chemical dispensing mechanism remains inside the liquid when there are no bubbles present on the liquid surface, and is exposed from the inside of the liquid when there are bubbles present on the liquid surface.

Automatic analysis system

An automatic analysis device is provided with: a sample disk for holding a sample container that accommodates a sample; a reagent disk for holding a reagent container that accommodates a reagent; at least two different measuring units that respectively perform different types of analyses; a control part that controls the measuring units; and a display part that displays: a work flow area in which the flow of operation of the two or more measuring units is displayed; and an overview area in which the usable or unusable states of the respective measuring units are displayed, wherein the overview area has a unit necessity-of-use selection part that can select whether using each of the measuring units is necessary, and the control part controls the display part so as to change the display of the work flow area on the basis of the information set in the unit necessity-of-use selection part.

Addressing the problem of preventing contamination, the present invention is characterized by being provided with a reagent nozzle (H) for discharging a reagent (M) at a predetermined discharge pressure to a reaction vessel (V) in which a specimen (M) is accommodated, a control unit for controlling the horizontal position of the reagent nozzle (H) in accordance with the liquid amount of the reagent (M) and the viscosity of the reagent (M), a dispensing unit for dispensing the reagent (M) into the reaction vessel (V), and a photometer for detecting light radiated to a mixture of the specimen (M) and the reagent (M), the control unit setting the horizontal position of the reagent nozzle (H) to the center position of the reaction vessel (V) when the liquid amount of the reagent (M) is greater than the amount of the specimen (M) and the viscosity of the reagent (M) is equal to the viscosity of the specimen (M) or lower than the viscosity of the specimen (M).

The present invention makes it possible for an automated analyzer including two or more types of photometers to obtain suitable output of the measurement results of the plurality of photometers and suitable data alarm output even if there is an abnormality, or the like, at the time of measurement. This automated analyzer includes, for example, two types of photometers having different quantitative ranges and an analysis control unit for controlling analysis that includes measurement of a given sample using the two types of photometers. If two types of data alarms corresponding to abnormalities, or the like, during measurement have been added to the two types of measurement results from the two types of photometers, the analysis control unit selects measurement result and data alarm output corresponding to the combination of the two types of data alarms and outputs the same to a user as analysis results.

An automated analysis device includes: a first measurement unit having a reaction disc for retaining a plurality of reaction cells containing a mixed solution of sample and reagent on a circumference, a light source for irradiating the mixed solution contained in the reaction cells with light, and a light-receiving unit for detecting the irradiated light; a cleaning mechanism for cleaning the reaction cells having undergone measurement; disposable reaction containers for containing the mixed solution of sample and reagent; a second measurement unit that has a plurality of measurement channels for retaining the disposable reaction containers, and includes a light source for irradiating the disposable reaction containers retained in each of the plurality of measurement channels with light; a read unit for reading identification information; and a control unit for controlling an analysis condition for the sample on the basis of the information that has been read.

Automated analysis device

The automatic analysis device is provided with (1) a measurement mechanism having a light measuring unit having a reaction container in which the sample is dispensed, a light source which emits light to the reaction container, and a detection unit that detects scattered light from the sample in the reaction container, (2) an amplifier circuit unit having an adder-subtractor that adds or subtracts a correction signal to or from a first measurement signal from the detection unit, and an amplifier circuit which amplifies the output signal by the adder-subtractor at a fixed amplification rate to output a second measurement signal, and (3) an arithmetic operation unit which calculates the correction signal on the basis of a difference between the signal level of the second measurement signal and a target value, and which executes an analysis action based on the second measurement signal after correction by means of the correction signal.

Automatic analysis device, automatic analysis system, and automatic analysis method

In blood coagulation time measurement, the reaction time relies on the blood coagulation ability of a specimen and is not fixed. In particular, in module-type devices, errors may occur in the specimen processing, measurement number, and measurement time between a plurality of blood coagulation analysis units, leading to the risk of lowering the processing capability of the device as a whole. The present invention is a module-type automated analyzer provided with a plurality of blood coagulation analysis units capable of analyzing blood coagulation time items in which the reaction time between a specimen and a reagent differs depending on the specimen, wherein a control unit that controls the specimen rack conveying operation finds the total of forecasted measurement times of measurement items requested for specimens being analyzed and queued specimens in each of the plurality of blood coagulation analysis units, and determines the conveyance destination of the specimen rack on the basis of the total of the forecasted measurement times that was found.

Automated analyzer

The purpose of the present invention is to provide an automatic analysis device capable of efficiently performing a plurality of analyses, while reducing the footprint and cost of the device. Provided is an automatic analysis device characterized by being provided with containers for containing samples, one rack for placing the containers thereon, and a control unit, the control unit generating, with respect to the one rack, a plurality of registration patterns in which information of the positions where the containers are disposed, and information of the samples contained in the containers are correlated with each other, storing the registration patterns thus generated, applying, to the one rack, one registration pattern selected from among the registration patterns thus stored, and analyzing the samples. Also provided is an analysis method using the device.

The purpose of the present invention is to provide an automatic analysis device that combines a biochemical analysis unit and a blood coagulation analysis unit and has a high processing capacity while reducing device cost and life-cycle cost. An automatic analysis device is characterized in that when a synthetic-substrate item or latex-agglutination item from among synthetic-substrate, latex-agglutination, and clotting-time blood-coagulation-test items is made to be a first test item and the clotting-time item is made to be a second test item, if there is a measurement request for the first test item and second test item in the same specimen rack, a control unit determines the conveyance path of the specimen rack such that the first test item is measured using a biochemical analysis unit and the second test item is measured using a coagulation time analysis unit and controls a conveyance line.

A signal reference value (SLocal) is set at which a blood coagulation reaction time (T) of a blood coagulation time reference sample measured on the basis of the result of comparing a signal value (amount of transmitted light, amount of scattered light, amount of fluorescence, or turbidity) pertaining to blood coagulation time that varies temporally according to the mixing and reaction of the blood coagulation time reference sample and a reagent and a signal reference value (S) corresponds to an expected value (Te) for the blood coagulation reaction time that has been set beforehand so as to correspond to the blood coagulation time reference sample. As a result, it is possible to use the blood coagulation time reference sample to determine the state of the reagent and enhance the reliability of measurement results by setting a unique signal reference value for each reagent container.

Growing community of inventors

Tokyo, Japan

Chie Yabutani