Tsinghua University

Mackay Memorial Hospital

Mackay Memorial Hosptal

Chie-Pein Chen

Szu-Ying Chen

Chien-Chong Hong

Yeou-Ping Tsao

Jia-Cherng Horng

Kuen-Der Yang

Disclosed herein is a formulation comprising an extracellular vesicle (EV), and a therapeutic active agent induced or embedded in the EV. According to preferred embodiments of the present disclosure, the EV is isolated from umbilical cord mesenchymal stem cells, and the active agent may be a growth factor, an immune-modulating agent, a small molecule, an siRNA, cDNA or a plant ingredient; for example, curcumin. Also disclosed herein are methods for producing the present formulation, and uses of the present formulation in the treatment of various diseases.

Formulation comprising extracellular vesicles, method for producing the same, and uses thereof

The present invention is a C-reactive protein imprinted polymer film. The C-reactive protein antibody imprinted polymer film comprises a plurality of imprinted nanocavities with unified orientation and distribution formed by removing a plurality of C-reactive proteins from a polymer film. Its ability to capture the target proteins can achieve 99% compared with the natural antibodies. The present invention further provides a C-reactive protein microchip system formed by the dynamic capacitance sensing method with the above imprinted polymer film. The C-reactive protein microchip system comprises a body having a first chamber and a second chamber, and a detector.

C-reactive protein imprinted polymer film and microchip system utilizing the same

Growing community of inventors

Taipei, Taiwan

Chie-Pein Chen