Kabushiki Kaisha Komatsu Seisakusho

Agc Inc.

Chiaki Kojima

Hiroshi Ohta

Akira Nemoto

Mitsuteru Motomura

Alimjan Idiris

Hiromichi Kumagai

Hidekazu Aoki

To provide a method for producing transferrin by secretion with high productivity using a transformant of, and a transformant suitable for the method. A transformant usingas a host, comprising a transferrin gene and a secretion signal peptide gene expressing transferrin to which a secretion signal peptide which functions in the host binds, located in an upstream region of the transferrin gene, and having gas2 gene endogenous to the host deleted or inactivated; and a method for producing transferrin, which comprises culturing the transformant in a liquid medium and obtaining transferrin from the liquid medium.

Transformant, and method for producing transferrin

Such a ground excavating apparatus that conducts excavation of a soft stratum by means of a bucket and employs an impact crusher for the excavation of such a hard stratum as a rock bed or the like is disclosed. Introduced in the present application is a ground excavator of such a category that comprises a housing, a bucket boom properly set in place in the said housing in a manner of being capable of traveling forward and rearward, a bucket properly fitted in place on the front end section of the said bucket boom in a manner of being capable of inclining, and an impact crushing mechanism well capable of traveling forward and rearward by virtue of a hydraulic jack housed in the said bucket boom, and employs the said bucket and the said impact crushing mechanism in an alternate manner to best suit the nature of the ground to be excavated.

Ground excavating apparatus

Tunnel excavator for forming an upper half annular hollow space in the solid earth. The excavator has an arch shaped shield provided with a plurality of chambers in which excavating machines are located. Each of the excavating machines is swingably supported in the respective chamber and gripper means for securely abutting against the outer and inner surfaces of the solid earth formed by the upper half annular hollow space is located in each of the chambers. Thrust generating means is connected between the respective excavating machines and the respective gripper means so that the excavating machines can be advanced by the action of the thrust generating means when the gripper means is actuated to abut against the earth.

Tunnel excavator

Growing community of inventors

Tokyo, Japan

Chiaki Kojima