Elc Management LLC

E-l Management Corporation

Chia Wen Chen

Thomas Mammone

Mindy S Goldstein

David Gan

Paul Edward Stamets

Kenneth D Marenus

Christina G Fthenakis

Andrew Weil

The present invention comprises cosmetic compositions and methods for retarding hair growth comprising a combination of an ornithine decarboxylase inhibitor, an anti-angiogenic active and an anti-inflammatory.

Cosmetic composition and method for retarding hair growth

Disclosed are topical compositions comprising extracts ofin amounts that are effective to influence LTB4-mediated chemotaxis and/or IL-1&#x3b2; mediated adhesion of polymorphonuclear leukocytes. Theextract may be used alone or in combination with secondary anti-inflammatory and skin active agents, such as other mushroom and/or natural extracts. The secondary anti-inflammatory agents may or may not function by antagonizing LTB4-mediated chemotaxis and IL-1&#x3b2; mediated adhesion. The extract may be incorporated into a cosmetically acceptable vehicle. The present invention includes methods of treating skin inflammation by applying to inflamed skin, anti-inflammatory effective amounts ofextract in a defined treatment regimen.

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A cosmetic composition comprising a UV-protective amount of at least one rosavin, preferably present in an extract ofin a cosmetically acceptable vehicle, and methods of use thereof, including preventing or reducing the signs of photoaging.

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New Rochelle, NY, United States of America

Chia Wen Chen