Amgen Inc.

Chia-Jung Wu

Wael Mismar

Shaun Robert Devitt

Jessica Hai Liu

Anthony Bitong

Malak Guirguis

Kenneth G Schalhoub

Dylan Bourelle

Robert W Swift

Nicholas J Clark

Ren-Yo Forng

Mads Schjoth Due

Mingda Eu

Cheng-Chieh Chou

Rami Saifan

Tej Desai

Arin Keshishian

Chelsea Balli-Cruz

Heather N Franey

Pierre Burquel

Ryan Oba

Ronak Maheshwari

Olivia Alice Henderson

Shermeen A Abbas

A drug delivery system includes a delivery container, a first drug insertion port, at least one additional drug insertion port, and an IV connection port. The delivery container includes upper, lower, first side, and second side portions, and further includes a tapered region extending between the first side portion and the second side portion. The first drug insertion port is positioned at the lower portion of the delivery container and has a first coupling mechanism. The at least one additional drug insertion port is also positioned at the lower portion of the delivery container, but includes a second coupling mechanism that is different than the first coupling mechanism. The IV connection port is positioned at the lower portion of the delivery container adjacent to a lower portion of the tapered region.

Dosing systems and approaches

A method of externally sterilizing a drug delivery device utilizing Nitrogen Dioxide (NO2) is provided, including placing the drug delivery device in a sterilization chamber, introducing into the chamber a dose of NO2 having a concentration of between about 2 and 20 milligrams per Liter by applying a vacuum level of between about 10 and 600 Torr and holding the vacuum level for a dwell time of between about 2 and 20 minutes, repeating the step of introducing into the chamber a dose of NO2 for a number of pulses between about 1 and 24, purging the sterilization chamber of at least substantially all of the NO2, and aerating the sterilization chamber.

Method for external sterilization of drug delivery device

An injection device is provided, including a syringe having a barrel and a flange and a backstop configured to be coupled with the syringe adjacent to the flange. The backstop includes an inner surface generally extending around at least a portion of the syringe, wherein the inner surface includes at least one protrusion extending away from the inner surface and configured to engage the flange and/or the barrel to permit or promote airflow through a space between the inner surface and the syringe.

Injection device for drug delivery and packaging for the injection device

Growing community of inventors

Redondo Beach, CA, United States of America

Chia-Jung Wu