National Yang Ming Chiao Tung University

Other

Industrial Technology Research Institute

National Health Research Institutes

Scinopharm Taiwan, Ltd.

Chang Gung Medical Foundation Keelung Chang Gung Memorial Hospital

Chi-Ying Huang

Pan-Chyr Yang

Yu-Wen Liu

Tzu-Ling Tseng

Shih-Lan Hsu

Hardy W Chan

Jane Hsiao

Chi-Tai Yeh

Chun-Hung Wu

Hui-Chu Hsieh

Tse-Hung Huang

Meng-Hua Lee

Hsuan-Min Hsu

Kuan-Ting Lin

Li-Jen Su

The present invention is directed to therapeutic methods and compositions for treating non-small cell lung cancer in a subject comprising administering an effective amount of an extract or powder of a herbal mixture, optionally with an anti-cancer agent to said subject. The herbal mixture comprises a component of at least one species from each of the genus-Red,-White,--Red, and

Methods and compositions for treating non-small cell lung cancer

The present invention relates to use of antipsychotic phenothiazine derivative for treatment of cancer. The invention also provides a use for manufacture a medicament, a pharmaceutical composition and a method for treating a cancer, and/or preventing or delaying cancer recurrence based on trifluoperazine. The invention further provides a use for manufacture a medicament, a pharmaceutical composition and a method for treating cancer based on thioridazine and its enantiomers. Additionally, the invention provides a use for manufacture a medicament, a pharmaceutical composition and a method for treating KRAS mutant NSCLC comprising thioridazine.

Pharmaceutical composition for treatment of cancer using phenothiazine

The present invention relates to a new approach for treating a cancer or fibrosis, such as hepatocellular carcinoma, or liver fibrosis using an extract from a plant ofsp.,sp., orsp., and prepared by extracting the plant with dimethyl sulfoxide (DMSO), its fraction or the compound isolated from the extract.

Anti-cancer extract and compounds

The present disclosure relates to a method for selecting a pool of molecules comprising detecting if the pool of molecules has binding specificity to an agent. A method for selecting a pool of biological markers in or on a cell, a composition comprising a pool of molecules, a method for delivering a therapeutic agent, and a method for diagnosing a condition in a subject are also provided.

Method of using antibody-liposome complexes for selecting a pool of molecules

The present invention provides a method for inhibiting the growth of cancer stem cells, particularly colorectal cancer stem cells, liver cancer stem cells, lung cancer stem cells or breast cancer stem cells, comprising administering to a subject in need thereof a therapeutically effective amount of a compound of antimycin A or a pharmaceutically acceptable salt thereof, together with a pharmaceutically acceptable carrier.

Method of using antimycin A to downregulate Wnt/b-catenin pathway to treat gefitinib resistant cancer

The preset invention relates to a new approach for treating a cancer or fibrosis, such as Hepatocellular carcinoma, or liver fibrosis using an extract from a plant ofsp.,sp. orsp., and prepared by extracting the plant with Dimethyl sulfoxide (DMSO), its fraction or the compound isolated from the extract.

The present invention provides a method for detecting liver fibrotic injury, including fibrosis and/or cirrhosis, by assaying biological samples for differential expression of at least one gene encoding a protein chosen from SEQ ID NO: 1-SEQ ID NO: 63 and human orthologs thereof, wherein differential expression of at least one gene suggests the presence of liver fibrosis or cirrhosis. The invention also provides a kit containing nucleic acid probes or antibodies for detecting liver fibrosis and/or cirrhosis by assaying the differential expression of proteins encoded by SEQ ID NO: 1-SEQ ID NO: 63 and human orthologs thereof.

Growing community of inventors

Taipei, Taiwan

Chi-Ying Huang