Medimmune Limited

Humabs Biomed Sa

Medlmmune Limited

Chew-shun Chang

Partha S Chowdhury

Christine Tkaczyk

Peter Pavlik

Lei Hua

Rebecca Buonpane

Davide Corti

Charles K Stover

Bret Sellman

Xiaodong Xiao

Martina Beltramello

Elisabetta Cameroni

Qun Wang

Meghan Pennini

Gilad Kaplan

Jamese Johnson Hilliard

Brett R Sellman

The present disclosure provides binding proteins (e.g., antibodies or antigen binding fragments thereof) that specifically bind toO1 and induce opsonophagocytic killing of(e.g.,). The present disclosure also provides methods of reducing(e.g.,) or treating or preventing(e.g.,) infection in a subject comprising administering theO1 binding proteins, (e.g., antibodies or antigen-binding fragments thereof) to the subject.

Anti-O1 antibodies and uses thereof

Antibodies and antigen binding fragments thereof directed against() surface determinant antigens and secreted toxins are disclosed. Methods of detecting, diagnosing and treatingusing the antibodies and antigen binding fragments thereof are also provided.

[object Object]

Antibodies tosurface determinants

Growing community of inventors

Gaithersburg, MD, United States of America

Chew-shun Chang