Allergan, Inc.

Chetan Pujara

Anuradha V Gore

John T Trogden

Adnan K Salameh

Sukhon Likitlersuang

Ajay P Parashar

William F Kelly

Rhett M Schiffman

Jaya Giyanani

Robert S Jordan

Kevin Krock

Jie Shen

Sesha Neervannan

Marina Bejanian

Kristin B Prinn

Richard S Graham

Jane-Guo Shiah

Kevin S Warner

Mayssa Attar

Pramod Sarpotdar

Sai Shankar

Andrea S Kim

Ronald Bradford

Ke Wu

Aileen Morgan

Guang Wei Lu

Mu-Lan Lee

Hao Hou

Melissa Gulmezian

Ramakrishnan Srikumar

The present invention provides ophthalmic compositions, e.g. artificial tears, suitable for treating dry eye syndrome in a human or other mammal suffering there from, e.g. a dog or cat, which comprise a mixture of castor oil with another oil, e.g. a food oil, e.g. olive oil, sesame oil, corn oil etc.

Artificial tears and therapeutic uses

The disclosure provides compositions for treating an ocular condition. The composition comprises a physiologically effective amount of an androgen, wherein the composition is suitable for topical administration to an eye. The disclosure further provides methods for treating an ocular condition with the disclosed compositions.

Androgen composition for treating an ophthalmic condition

The present invention is directed to preservative-free solutions of brimonidine and timolol for lowering intra-ocular pressure and treatment of glaucoma.

Preservative free brimonidine and timolol solutions

Disclosed herein are emulsions comprising testosterone or related androgens, castor oil, cyclodextrin, Pemulen TR-2, Polyoxyl 40, and other ingredients. The compositions are useful for treating keratoconjunctivitis sicca and meibomian gland disease.

Non-irritating testosterone emulsions

The present disclosure relates to suspension formulations and systems for the treatment of ocular conditions. The suspension formulations can include cyclosporin A and in some embodiments, Form 1 or Form 2 cyclosporin A. A delivery system can be provided that includes two parts, a first part containing particles of cyclosporin and a second part containing other components that can be combined with the first part to make a suspension formulation. The suspension can be injected into the subconjunctival or other periocular space to treat ocular conditions, such as dry eye disease.

Suspension compositions of cyclosporin A for subconjunctival and periocular injection

Ophthalmic products and related methods are described herein. These methods include a stabilizing composition comprising a therapeutically active agent which is separated from a liquid vehicle composition by a barrier. The barrier may be removed to allow the two compositions to mix to provide an ophthalmically acceptable liquid comprising the therapeutically active agent.

Two part formulation system for ophthalmic delivery

Biocompatible intraocular implants may include a brimonidine free base and a biodegradable polymer associated with the brimonidine free base to facilitate the release of the brimonidine free base into an eye with the polymer matrix lasts a period of time of not more than twice the drug release duration, but more than the drug release duration.

Sustained drug delivery implant

The present invention is directed to preservative-free solutions of bimatoprost and timolol for lowering intraocular pressure and treatment of glaucoma.

Preservative free bimatoprost and timolol solutions

Methods and compositions for stimulating the growth of hair are disclosed wherein said compositions include a cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl compound represented by the formula I 

Topical compositions comprising bimatoprost and methods for stimulating hair growth therewith

Disclosed herein are compositions for lowering intraocular pressure (IOP) of an eye comprising a combination IOP-lowering agents bimatoprost, brimonidine, and timolol. Further disclosed are methods for reducing IOP in the eye of a subject.

Compositions and methods for lowering intraocular pressure

Compositions and methods for stimulating hair growth

The present invention is directed to preservative-free solutions of bimatoprost and timolol for lowering intra-ocular pressure and treatment of glaucoma.

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Irvine, CA, United States of America

Chetan Pujara